Genular: Defining Cellular Identity and Function

Details for: Lgals1

Gene ID: 16852

Symbol: Lgals1

Ensembl ID: ENSMUSG00000068220

Description: lectin, galactose binding, soluble 1

Associated with

Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Apoptotic process
(GO:0006915)
Carbohydrate binding
(GO:0030246)
Cell-cell adhesion
(GO:0098609)
Cell surface
(GO:0009986)
Collagen-containing extracellular matrix
(GO:0062023)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Galactose binding
(GO:0005534)
Galectin complex
(GO:1990724)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
(GO:0007157)
Identical protein binding
(GO:0042802)
Lactose binding
(GO:0030395)
Laminin binding
(GO:0043236)
Maintenance of protein location
(GO:0045185)
Myoblast differentiation
(GO:0045445)
Negative regulation of cell-substrate adhesion
(GO:0010812)
Negative regulation of neuron projection development
(GO:0010977)
Plasma cell differentiation
(GO:0002317)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of erythrocyte aggregation
(GO:0034120)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of viral entry into host cell
(GO:0046598)
Protein binding
(GO:0005515)
T cell costimulation
(GO:0031295)

Other Information

Proteins

Galectin-1

Genular Protein ID: 796472176

Symbol: LEG1_MOUSE

Name: Galectin-1

UniProtKB Accession Codes:

P16045 P05163 P11946 P17601 Q4FZH4 Q99M27 Q9D0X0

Database IDs:

Citations:

PubMed ID: 2803247

Title: The sequence of the mouse 14 kDa beta-galactoside-binding lectin and evidence for its synthesis on free cytoplasmic ribosomes.

PubMed ID: 2803247

DOI: 10.1042/bj2610847

PubMed ID: 2025648

Title: Structure and expression of the negative growth factor mouse beta-galactoside binding protein gene.

PubMed ID: 2025648

DOI: 10.1016/0167-4781(91)90084-y

PubMed ID: 1986871

Title: Identification of an autocrine negative growth factor: mouse beta-galactoside-binding protein is a cytostatic factor and cell growth regulator.

PubMed ID: 1986871

DOI: 10.1016/0092-8674(91)90211-g

PubMed ID: 1638977

Title: Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre- and post-implantation development.

PubMed ID: 1638977

DOI: 10.1242/dev.115.1.143

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2335567

Title: Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism.

PubMed ID: 2335567

DOI: 10.1083/jcb.110.5.1681

PubMed ID: 3335026

Title: Expression of two different endogenous galactoside-binding lectins sharing sequence homology.

PubMed ID: 3335026

PubMed ID: 3020551

Title: Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes.

PubMed ID: 3020551

DOI: 10.1073/pnas.83.20.7603

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 135
Mass: 14866
Checksum: FD6967C1F4117122
Sequence:

MACGLVASNL NLKPGECLKV RGEVASDAKS FVLNLGKDSN NLCLHFNPRF NAHGDANTIV 
CNTKEDGTWG TEHREPAFPF QPGSITEVCI TFDQADLTIK LPDGHEFKFP NRLNMEAINY 
MAADGDFKIK CVAFE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lgals1

Associated with

Other Information

The sequence of the mouse 14 kDa beta-galactoside-binding lectin and evidence for its synthesis on free cytoplasmic ribosomes. PubMed ID: 2803247

Structure and expression of the negative growth factor mouse beta-galactoside binding protein gene. PubMed ID: 2025648

Identification of an autocrine negative growth factor: mouse beta-galactoside-binding protein is a cytostatic factor and cell growth regulator. PubMed ID: 1986871

Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre- and post-implantation development. PubMed ID: 1638977

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism. PubMed ID: 2335567

Expression of two different endogenous galactoside-binding lectins sharing sequence homology. PubMed ID: 3335026

Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes. PubMed ID: 3020551

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337