Genular: Defining Cellular Identity and Function

Details for: Lhcgr

Gene ID: 16867

Symbol: Lhcgr

Ensembl ID: ENSMUSG00000024107

Description: luteinizing hormone/choriogonadotropin receptor

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Hormone ligand-binding receptors
(R-MMU-375281)
Signaling by gpcr
(R-MMU-372790)
Activation of adenylate cyclase activity
(GO:0007190)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Arachidonic acid secretion
(GO:0050482)
Atpase binding
(GO:0051117)
Cellular response to gonadotropin stimulus
(GO:0071371)
Cellular response to luteinizing hormone stimulus
(GO:0071373)
Centriolar satellite
(GO:0034451)
Choriogonadotropin hormone binding
(GO:0038106)
Choriogonadotropin hormone receptor activity
(GO:0035472)
Cognition
(GO:0050890)
Development of secondary male sexual characteristics
(GO:0046544)
Endosome
(GO:0005768)
Extracellular space
(GO:0005615)
Female gonad development
(GO:0008585)
G protein-coupled peptide receptor activity
(GO:0008528)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone-mediated signaling pathway
(GO:0009755)
Identical protein binding
(GO:0042802)
Luteinizing hormone receptor activity
(GO:0004964)
Luteinizing hormone signaling pathway
(GO:0042700)
Male gonad development
(GO:0008584)
Membrane
(GO:0016020)
Ovarian follicle development
(GO:0001541)
Ovulation cycle process
(GO:0022602)
Peptide hormone binding
(GO:0017046)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of calcium-mediated signaling
(GO:0050850)
Positive regulation of calcium ion transport into cytosol
(GO:0010524)
Positive regulation of hormone biosynthetic process
(GO:0046886)
Positive regulation of inositol trisphosphate biosynthetic process
(GO:0032962)
Positive regulation of release of sequestered calcium ion into cytosol
(GO:0051281)
Protein-hormone receptor activity
(GO:0016500)
Protein targeting to lysosome
(GO:0006622)
Receptor complex
(GO:0043235)
Regulation of steroid hormone biosynthetic process
(GO:0090030)
Response to luteinizing hormone
(GO:0034699)
Seminiferous tubule development
(GO:0072520)
Signal transduction
(GO:0007165)
Spermatogenesis
(GO:0007283)
Uterus development
(GO:0060065)

Other Information

Proteins

Lutropin-choriogonadotropic hormone receptor

Genular Protein ID: 3169521410

Symbol: LSHR_MOUSE

Name: Lutropin-choriogonadotropic hormone receptor

UniProtKB Accession Codes:

P30730

Database IDs:

Citations:

PubMed ID: 1311310

Title: Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphoinositide breakdown and Ca2+ mobilization. Studies with the cloned murine luteinizing hormone receptor expressed in L cells.

PubMed ID: 1311310

DOI: 10.1016/s0021-9258(18)42858-x

PubMed ID: 1459341

Title: The murine luteinizing hormone and follicle-stimulating hormone receptor genes: transcription initiation sites, putative promoter sequences and promoter activity.

PubMed ID: 1459341

DOI: 10.1016/0303-7207(92)90009-u

Sequence Information:

Length: 700
Mass: 78215
Checksum: 8A6840A011E1E014
Sequence:

MGRRVPALRQ LLVLAMLVLK QSQLHSPELS GSRCPEPCDC APDGALRCPG PRAGLARLSL 
TYLPVKVIPS QAFRGLNEVV KIEISQSDSL ERIEANAFDN LLNLSEILIQ NTKNLLYIEP 
GAFTNLPRLK YLSICNTGIR TLPDVSKISS SEFNFILEIC DNLYITTIPG NAFQGMNNES 
ITLKLYGNGF EEVQSHAFNG TTLISLELKE NIYLEKMHSG TFQGATGPSI LDVSSTKLQA 
LPSHGLESIQ TLIATSSYSL KTLPSREKFT SLLVATLTYP SHCCAFRNLP KKEQNFSFSI 
FENFSKQCES TVREANNETL YSAIFEENEL SGWDYDYDFC SPKTLQCTPE PDAFNPCEDI 
MGYAFLRVLI WLINILAIFG NLTVLFVLLT SRYKLTVPRF LMCNLSFADF CMGLYLLLIA 
SVDSQTKGQY YNHAIDWQTG SGCSAAGFFT VFASELSVYT LTVITLERWH TITYAVQLDQ 
KLRLRHAIPI MLGGWIFSTL MATLPLVGVS SYMKVSICLP MDVESTLSQV YILSILLLNA 
VAFVVICACY VRIYFAVQNP ELTAPNKDTK IAKKMAILIF TDFTCMAPIS FFAISAAFKV 
PLITVTNSKV LLVLFYPVNS CANPFLYAVF TKAFQRDFFL LLSRFGCCKH RAELYRRKEF 
SACTFNSKNG FPRSSKPSQA ALKLSIVHCQ QPTPPRVLIQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.