Genular: Defining Cellular Identity and Function

Details for: Lipa

Gene ID: 16889

Symbol: Lipa

Ensembl ID: ENSMUSG00000024781

Description: lysosomal acid lipase A

Associated with

Ldl clearance
(R-MMU-8964038)
Plasma lipoprotein assembly, remodeling, and clearance
(R-MMU-174824)
Plasma lipoprotein clearance
(R-MMU-8964043)
Transport of small molecules
(R-MMU-382551)
Acute inflammatory response
(GO:0002526)
Adaptive thermogenesis
(GO:1990845)
Adipose tissue development
(GO:0060612)
Atp biosynthetic process
(GO:0006754)
Blood vessel endothelial cell differentiation
(GO:0060837)
Bone marrow development
(GO:0048539)
Cell morphogenesis
(GO:0000902)
Cell population proliferation
(GO:0008283)
Cell proliferation in bone marrow
(GO:0071838)
Cellular lipid biosynthetic process
(GO:0097384)
Cellular lipid metabolic process
(GO:0044255)
Cholesterol biosynthetic process
(GO:0006695)
Cholesterol efflux
(GO:0033344)
Cholesterol metabolic process
(GO:0008203)
Cholesterol storage
(GO:0010878)
Cholesterol transport
(GO:0030301)
Common myeloid progenitor cell proliferation
(GO:0035726)
Cytokine production
(GO:0001816)
Cytosol
(GO:0005829)
Defecation
(GO:0030421)
Determination of adult lifespan
(GO:0008340)
Endocytosis
(GO:0006897)
Endosome to lysosome transport
(GO:0008333)
Endothelial cell proliferation
(GO:0001935)
Energy homeostasis
(GO:0097009)
Epithelial cell proliferation
(GO:0050673)
Fat cell proliferation
(GO:0070341)
Fatty acid metabolic process
(GO:0006631)
Fibrillar center
(GO:0001650)
Gene expression
(GO:0010467)
Glucose metabolic process
(GO:0006006)
Glycolytic process
(GO:0006096)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Hemopoiesis
(GO:0030097)
Homeostasis of number of cells
(GO:0048872)
Homeostasis of number of cells within a tissue
(GO:0048873)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on ester bonds
(GO:0016788)
Inflammatory response
(GO:0006954)
Intracellular membrane-bounded organelle
(GO:0043231)
Lipase activity
(GO:0016298)
Lipid catabolic process
(GO:0016042)
Lipid homeostasis
(GO:0055088)
Lipid import into cell
(GO:0140354)
Lipid metabolic process
(GO:0006629)
Lipid storage
(GO:0019915)
Lipoprotein catabolic process
(GO:0042159)
Liver development
(GO:0001889)
Liver morphogenesis
(GO:0072576)
Lung development
(GO:0030324)
Lysosome
(GO:0005764)
Lysosome organization
(GO:0007040)
Macrophage homeostasis
(GO:0061519)
Mitochondrion organization
(GO:0007005)
Mitotic cell cycle
(GO:0000278)
Multicellular organismal-level chemical homeostasis
(GO:0140962)
Multicellular organismal-level homeostasis
(GO:0048871)
Myeloid cell apoptotic process
(GO:0033028)
Myeloid cell differentiation
(GO:0030099)
Neutral lipid metabolic process
(GO:0006638)
Nucleoplasm
(GO:0005654)
Organic substance metabolic process
(GO:0071704)
Positive regulation of t cell receptor signaling pathway
(GO:0050862)
Programmed cell death
(GO:0012501)
Reactive oxygen species biosynthetic process
(GO:1903409)
Regulation of membrane potential
(GO:0042391)
Regulation of mitochondrial membrane potential
(GO:0051881)
Respiratory burst involved in inflammatory response
(GO:0002536)
Response to cold
(GO:0009409)
Response to dietary excess
(GO:0002021)
Response to lipid
(GO:0033993)
Response to rapamycin
(GO:1901355)
Response to vitamin a
(GO:0033189)
Response to xenobiotic stimulus
(GO:0009410)
Retinoid metabolic process
(GO:0001523)
Small gtpase-mediated signal transduction
(GO:0007264)
Spleen development
(GO:0048536)
Sterol esterase activity
(GO:0004771)
Sterol metabolic process
(GO:0016125)
T cell apoptotic process
(GO:0070231)
T cell differentiation
(GO:0030217)
T cell proliferation
(GO:0042098)
Tissue remodeling
(GO:0048771)
Tor signaling
(GO:0031929)
Triglyceride-rich lipoprotein particle clearance
(GO:0071830)
Triglyceride metabolic process
(GO:0006641)
Vitamin a metabolic process
(GO:0006776)

Other Information

Proteins

Lysosomal acid lipase/cholesteryl ester hydrolase
Q3TEL5_MOUSE

Genular Protein ID: 1020558407

Symbol: LICH_MOUSE

Name: Lysosomal acid lipase/cholesteryl ester hydrolase

UniProtKB Accession Codes:

Q9Z0M5 Q8C2G7

Database IDs:

Citations:

PubMed ID: 8725147

Title: Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein.

PubMed ID: 8725147

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 397
Mass: 45325
Checksum: 866B123A1A058134
Sequence:

MQLQGLVFVF TIGILLSRVP TGTVSAVDPE VNMNVTEIIM RWGYPGEEHS VLTGDGYILS 
IHRIPRGRKN HFGKGPRPVV YLQHGLLADS SNWVTNIDNS SLGFLLADAG FDVWMGNSRG 
NTWSLKHKTL SVSQDEFWAF SFDEMAKYDL PASINYILNK TGQEQIYYVG HSQGCTIGFI 
AFSQMPELAK KIKMFLVLAP VLSLNFASGP LLQLGRLPDP LLKDMFGQKQ FLPQSAMLKW 
LSIHVCTHVI MKELCANVFF LLCGFNEKNL NMSRVDVYTT HCPAGTSVQN MLHWGQVFKY 
RKLQAFDWGS SEKNYFHYNQ SFPPSYNIKN MRLPTALWSG GRDWLADIND ITILLTQIPK 
LVYHKNIPEW DHLDFIWGLD APWKLYDEII SLMKKYQ

Genular Protein ID: 4129653166

Symbol: Q3TEL5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TEL5

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 397
Mass: 45309
Checksum: 4C6857C81A021EC1
Sequence:

MQLQGLVFVF TIGILLSRVP TGTVSAVVPE VNMNVTEIIM RWGYPGEEHS VLTGDGYILS 
IHRIPRGRKN HFGKGPRPVV YLQHGLLADS SNWVTNIDNS SLGFLLADAG FDVWMGNSRG 
NTWSLKHKTL SVSQDEFWAF SFDEMAKYDL PASINYILNK TGQEQIYYVG HSQGCTIGFI 
AFSQMPELAK KIKMFLVLAP VLSLNFASGP LLQLGRLPDP LLKDMFGQKQ FLPQSAMLKW 
LSIHVCTHVI MKELCANVFF LLCGFNEKNL NMSRVDVYTT HCPAGTSVQN MLHWGQVFKY 
RKLQAFDWGS SEKNYFHYNQ SFPPSYNIKN MRLPTALWSG GRDWLADIND ITILLTQIPK 
LVYHKNIPEW DHLDFIWGLD APWKLYDEII SLMKKYQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lipa

Associated with

Other Information

Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein. PubMed ID: 8725147

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073