Details for: Lipe

Gene ID: 16890

Symbol: Lipe

Ensembl ID: ENSMUSG00000003123

Description: lipase, hormone sensitive

Associated with

Other Information

Genular Protein ID: 3307895681

Symbol: LIPS_MOUSE

Name: Hormone-sensitive lipase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7698747

Title: Isolation and characterization of the gene for mouse hormone-sensitive lipase.

PubMed ID: 7698747

DOI: 10.1006/geno.1994.1614

PubMed ID: 9060404

Title: Hormone-sensitive lipase (Lipe): sequence analysis of the 129Sv mouse Lipe gene.

PubMed ID: 9060404

DOI: 10.1007/s003359900363

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15550674

Title: Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.

PubMed ID: 15550674

DOI: 10.1126/science.1100747

PubMed ID: 15878856

Title: Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes.

PubMed ID: 15878856

DOI: 10.1074/jbc.m414222200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19717842

Title: Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins.

PubMed ID: 19717842

DOI: 10.1074/jbc.m109.006726

PubMed ID: 19921680

Title: The stoichiometry of protein phosphorylation in adipocyte lipid droplets: analysis by N-terminal isotope tagging and enzymatic dephosphorylation.

PubMed ID: 19921680

DOI: 10.1002/pmic.200800861

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20625037

Title: Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.

PubMed ID: 20625037

DOI: 10.1194/jlr.m004259

PubMed ID: 21454566

Title: Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

PubMed ID: 21454566

DOI: 10.1074/jbc.m110.215434

PubMed ID: 23066022

Title: Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.

PubMed ID: 23066022

DOI: 10.1074/jbc.m112.400416

PubMed ID: 23291629

Title: Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.

PubMed ID: 23291629

DOI: 10.1038/nm.3056

Sequence Information:

  • Length: 759
  • Mass: 83348
  • Checksum: 3419AF52F6C85FF4
  • Sequence:
  • MDLRTMTQSL VTLAEDNMAF FSSQGPGETA RRLSNVFAGV REQALGLEPT LGQLLGVAHH 
    FDLDTETPAN GYRSLVHTAR CCLAHLLHKS RYVASNRKSI FFRASHNLAE LEAYLAALTQ 
    LRAMAYYAQR LLTINRPGVL FFEGDEGLTA DFLQEYVTLH KGCFYGRCLG FQFTPAIRPF 
    LQTLSIGLVS FGEHYKRNET GLSVTASSLF TGGRFAIDPE LRGAEFERII QNLDVHFWKA 
    FWNITEIEVL SSLANMASTT VRVSRLLSLP PEAFEMPLTS DPRLTVTISP PLAHTGPAPV 
    LARLISYDLR EGQDSKVLNS LAKSEGPRLE LRPRPHQAPR SRALVVHIHG GGFVAQTSKS 
    HEPYLKNWAQ ELGVPIFSID YSLAPEAPFP RALEECFFAY CWAVKHCDLL GSTGERICLA 
    GDSAGGNLCI TVSLRAAAYG VRVPDGIMAA YPVTTLQSSA SPSRLLSLMD PLLPLSVLSK 
    CVSAYSGTEA EDHFDSDQKA LGVMGLVQRD TSLFLRDLRL GASSWLNSFL ELSGRKPQKT 
    TSPTAESVRP TESMRRSVSE AALAQPEGLL GTDTLKKLTI KDLSNSEPSD SPEMSQSMET 
    LGPSTPSDVN FFLRPGNSQE EAEAKDEVRP MDGVPRVRAA FPEGFHPRRS SQGVLHMPLY 
    TSPIVKNPFM SPLLAPDSML KTLPPVHLVA CALDPMLDDS VMFARRLRDL GQPVTLKVVE 
    DLPHGFLSLA ALCRETRQAT EFCVQRIRLI LTPPAAPLN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.