Genular: Defining Cellular Identity and Function

Details for: Lmnb1

Gene ID: 16906

Symbol: Lmnb1

Ensembl ID: ENSMUSG00000024590

Description: lamin B1

Associated with

Apoptosis
(R-MMU-109581)
Apoptotic cleavage of cellular proteins
(R-MMU-111465)
Apoptotic execution phase
(R-MMU-75153)
Breakdown of the nuclear lamina
(R-MMU-352238)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Depolymerization of the nuclear lamina
(R-MMU-4419969)
Dna damage/telomere stress induced senescence
(R-MMU-2559586)
Formation of senescence-associated heterochromatin foci (sahf)
(R-MMU-2559584)
Initiation of nuclear envelope (ne) reformation
(R-MMU-2995383)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prophase
(R-MMU-68875)
M phase
(R-MMU-68886)
Nuclear envelope (ne) reassembly
(R-MMU-2995410)
Nuclear envelope breakdown
(R-MMU-2980766)
Programmed cell death
(R-MMU-5357801)
Rhod gtpase cycle
(R-MMU-9013405)
Rhof gtpase cycle
(R-MMU-9035034)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Cellular response to l-glutamate
(GO:1905232)
Double-stranded dna binding
(GO:0003690)
Heterochromatin formation
(GO:0031507)
Intermediate filament
(GO:0005882)
Jun kinase binding
(GO:0008432)
Lamin filament
(GO:0005638)
Nuclear envelope
(GO:0005635)
Nuclear envelope organization
(GO:0006998)
Nuclear inner membrane
(GO:0005637)
Nuclear lamina
(GO:0005652)
Nuclear matrix
(GO:0016363)
Nuclear membrane
(GO:0031965)
Nuclear migration
(GO:0007097)
Nuclear periphery
(GO:0034399)
Nuclear pore localization
(GO:0051664)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Phospholipase binding
(GO:0043274)
Positive regulation of g2/m transition of mitotic cell cycle
(GO:0010971)
Positive regulation of jnk cascade
(GO:0046330)
Protein localization to nuclear envelope
(GO:0090435)
Sequence-specific double-stranded dna binding
(GO:1990837)
Structural constituent of cytoskeleton
(GO:0005200)

Other Information

Proteins

Lamin-B1

Genular Protein ID: 575815745

Symbol: LMNB1_MOUSE

Name: Lamin-B1

UniProtKB Accession Codes:

P14733 Q61791

Database IDs:

Citations:

PubMed ID: 3243285

Title: Amino acid sequence and molecular characterization of murine lamin B as deduced from cDNA clones.

PubMed ID: 3243285

PubMed ID: 8586436

Title: Genomic structure of the mouse gene (Lmnb1) encoding nuclear lamin B1.

PubMed ID: 8586436

DOI: 10.1006/geno.1995.9868

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 588
Mass: 66786
Checksum: 3602BCE63588A32D
Sequence:

MATATPVQQQ RAGSRASAPA TPLSPTRLSR LQEKEELREL NDRLAVYIDK VRSLETENSA 
LQLQVTEREE VRGRELTGLK ALYETELADA RRALDDTARE RAKLQIELGK FKAEHDQLLL 
NYAKKESDLS GAQIKLREYE AALNSKDAAL ATALGDKKSL EGDLEDLKDQ IAQLEASLSA 
AKKQLADETL LKVDLENRCQ SLTEDLEFRK NMYEEEINET RRKHETRLVE VDSGRQIEYE 
YKLAQALHEM REQHDAQVRL YKEELEQTYH AKLENARLSS EMNTSTVNSA REELMESRMR 
IESLSSQLSN LQKESRACLE RIQELEDMLA KERDNSRRML SDREREMAEI RDQMQQQLSD 
YEQLLDVKLA LDMEISAYRK LLEGEEERLK LSPSPSSRVT VSRASSSRSV RTTRGKRKRV 
DVEESEASSS VSISHSASAT GNVCIEEIDV DGKFIRLKNT SEQDQPMGGW EMIRKIGDTS 
VSYKYTSRYV LKAGQTVTVW AANAGVTASP PTDLIWKNQN SWGTGEDVKV ILKNSQGEEV 
AQRSTVFKTT IPEEEEEEEE EPIGVAVEEE RFHQQGAPRA SNKSCAIM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lmnb1

Associated with

Other Information

Amino acid sequence and molecular characterization of murine lamin B as deduced from cDNA clones. PubMed ID: 3243285

Genomic structure of the mouse gene (Lmnb1) encoding nuclear lamin B1. PubMed ID: 8586436

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337