Genular: Defining Cellular Identity and Function

Details for: Xcl1

Gene ID: 16963

Symbol: Xcl1

Ensembl ID: ENSMUSG00000026573

Description: chemokine (C motif) ligand 1

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Ccr chemokine receptor binding
(GO:0048020)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to interleukin-4
(GO:0071353)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Cellular response to tumor necrosis factor
(GO:0071356)
Cellular response to type ii interferon
(GO:0071346)
Chemokine-mediated signaling pathway
(GO:0070098)
Chemokine activity
(GO:0008009)
Chemokine receptor binding
(GO:0042379)
Chemotaxis
(GO:0006935)
Cytokine activity
(GO:0005125)
Eosinophil chemotaxis
(GO:0048245)
Establishment of localization in cell
(GO:0051649)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
G protein-coupled receptor signaling pathway
(GO:0007186)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Lymphocyte chemotaxis
(GO:0048247)
Mature natural killer cell chemotaxis
(GO:0035782)
Monocyte chemotaxis
(GO:0002548)
Neutrophil chemotaxis
(GO:0030593)
Positive regulation of b cell chemotaxis
(GO:2000538)
Positive regulation of cd4-positive, alpha-beta t cell proliferation
(GO:2000563)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gtpase activity
(GO:0043547)
Positive regulation of immune response to tumor cell
(GO:0002839)
Positive regulation of immunoglobulin production in mucosal tissue
(GO:2000558)
Positive regulation of innate immune response
(GO:0045089)
Positive regulation of leukocyte chemotaxis
(GO:0002690)
Positive regulation of natural killer cell chemotaxis
(GO:2000503)
Positive regulation of neutrophil chemotaxis
(GO:0090023)
Positive regulation of t-helper 1 cell cytokine production
(GO:2000556)
Positive regulation of t-helper 2 cell cytokine production
(GO:2000553)
Positive regulation of t cell chemotaxis
(GO:0010820)
Positive regulation of t cell cytokine production
(GO:0002726)
Positive regulation of thymocyte migration
(GO:2000412)
Protein homodimerization activity
(GO:0042803)
Regulation of inflammatory response
(GO:0050727)
Release of sequestered calcium ion into cytosol
(GO:0051209)

Other Information

Proteins

Lymphotactin

Genular Protein ID: 2905540967

Symbol: XCL1_MOUSE

Name: Lymphotactin

UniProtKB Accession Codes:

P47993

Database IDs:

Citations:

PubMed ID: 7973732

Title: Lymphotactin: a cytokine that represents a new class of chemokine.

PubMed ID: 7973732

DOI: 10.1126/science.7973732

PubMed ID: 7875320

Title: Molecular cloning of a novel C or gamma type chemokine, SCM-1.

PubMed ID: 7875320

DOI: 10.1016/0014-5793(95)00093-o

PubMed ID: 9199871

Title: Murine lymphotactin: gene structure, post-translational modification and inhibition of expression by CD28 costimulation.

PubMed ID: 9199871

DOI: 10.1006/cyto.1996.0179

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21300913

Title: Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development.

PubMed ID: 21300913

DOI: 10.1084/jem.20102327

Sequence Information:

Length: 114
Mass: 12467
Checksum: 04B51A5FCC61763B
Sequence:

MRLLLLTFLG VCCLTPWVVE GVGTEVLEES SCVNLQTQRL PVQKIKTYII WEGAMRAVIF 
VTKRGLKICA DPEAKWVKAA IKTVDGRAST RKNMAETVPT GAQRSTSTAI TLTG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Xcl1

Associated with

Other Information

Lymphotactin: a cytokine that represents a new class of chemokine. PubMed ID: 7973732

Molecular cloning of a novel C or gamma type chemokine, SCM-1. PubMed ID: 7875320

Murine lymphotactin: gene structure, post-translational modification and inhibition of expression by CD28 costimulation. PubMed ID: 9199871