Genular: Defining Cellular Identity and Function

Details for: Ltb

Gene ID: 16994

Symbol: Ltb

Ensembl ID: ENSMUSG00000024399

Description: lymphotoxin B

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Tnfr2 non-canonical nf-kb pathway
(R-MMU-5668541)
Tnf receptor superfamily (tnfsf) members mediating non-canonical nf-kb pathway
(R-MMU-5676594)
Cytokine activity
(GO:0005125)
Extracellular space
(GO:0005615)
Gene expression
(GO:0010467)
Immune response
(GO:0006955)
Lymph node development
(GO:0048535)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of extrinsic apoptotic signaling pathway
(GO:2001238)
Positive regulation of interleukin-12 production
(GO:0032735)
Skin development
(GO:0043588)
Tumor necrosis factor receptor binding
(GO:0005164)

Other Information

Proteins

Lymphotoxin-beta

Genular Protein ID: 2204713227

Symbol: TNFC_MOUSE

Name: Lymphotoxin-beta

UniProtKB Accession Codes:

P41155

Database IDs:

Citations:

PubMed ID: 7846035

Title: Cloning and expression analysis of the murine lymphotoxin beta gene.

PubMed ID: 7846035

DOI: 10.1073/pnas.92.3.674

PubMed ID: 7995944

Title: Characterization of the mouse lymphotoxin-beta gene.

PubMed ID: 7995944

PubMed ID: 14656967

Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

PubMed ID: 14656967

DOI: 10.1101/gr.1736803

Sequence Information:

Length: 306
Mass: 32329
Checksum: B7D276AB84A22549
Sequence:

MGTRGLQGLG GRPQGRGCLL LAVAGATSLV TLLLAVPITV LAVLALVPQD QGRRVEKIIG 
SGAQAQKRLD DSKPSCILPS PSSLSETPDP RLHPQRSNAS RNLASTSQGP VAQSSREASA 
WMTILSPAAD STPDPGVQQL PKGEPETDLN PELPAAHLIG AWMSGQGLSW EASQEEAFLR 
SGAQFSPTHG LALPQDGVYY LYCHVGYRGR TPPAGRSRAR SLTLRSALYR AGGAYGRGSP 
ELLLEGAETV TPVVDPIGYG SLWYTSVGFG GLAQLRSGER VYVNISHPDM VDYRRGKTFF 
GAVMVG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.