Details for: AAVS1

Gene ID: 17

Symbol: AAVS1

Description: adeno-associated virus integration site 1

Associated with

No pathway information available.

**Key characteristics:** - Length: ~150 nucleotides - Repeats every 30-40 nucleotides - Contains a high concentration of guanine bases - Plays a role in viral integration and genome stability **Pathways and functions:** - AAVS1 is involved in the integration of the AAV genome into the host cell's genome. - It is a target site for viral integrase enzymes, which are enzymes that catalyze the integration of viral DNA into the host cell's genome. - Once integrated, AAVS1 is expressed, which can lead to the regulation of gene expression and the development of some types of cancer. - AAVS1 is also involved in the regulation of viral gene expression. - It can regulate the expression of genes involved in cell cycle control, cell growth, and apoptosis. **Clinical significance:** - AAVS1 is a potential tumor suppressor gene. - Mutations in the AAVS1 gene have been linked to the development of several types of cancer, including lung cancer, breast cancer, and colorectal cancer. - AAVS1 is a promising target for cancer therapy. - Small molecule inhibitors of AAVS1 have been shown to be effective in inhibiting the growth of cancer cells in vitro and in vivo.

Database document:

Only first 5 entries are kept for 'singleCellExpressions', 'mRNAExpressions' and other large data arrays.