Genular: Defining Cellular Identity and Function

Details for: Ltf

Gene ID: 17002

Symbol: Ltf

Ensembl ID: ENSMUSG00000032496

Description: lactotransferrin

Associated with

Antimicrobial peptides
(R-MMU-6803157)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metal sequestration by antimicrobial proteins
(R-MMU-6799990)
Neutrophil degranulation
(R-MMU-6798695)
Antibacterial humoral response
(GO:0019731)
Antifungal humoral response
(GO:0019732)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Bone morphogenesis
(GO:0060349)
Cell surface
(GO:0009986)
Cysteine-type endopeptidase inhibitor activity
(GO:0004869)
Cytolysis by host of symbiont cells
(GO:0051838)
Cytoplasm
(GO:0005737)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to gram-positive bacterium
(GO:0050830)
Early endosome
(GO:0005769)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Heparin binding
(GO:0008201)
Hydrolase activity
(GO:0016787)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Innate immune response in mucosa
(GO:0002227)
Iron ion binding
(GO:0005506)
Iron ion transport
(GO:0006826)
Killing of cells of another organism
(GO:0031640)
Lipopolysaccharide binding
(GO:0001530)
Membrane destabilizing activity
(GO:0140912)
Metal ion binding
(GO:0046872)
Monoatomic ion transport
(GO:0006811)
Negative regulation by host of viral process
(GO:0044793)
Negative regulation of atp-dependent activity
(GO:0032780)
Negative regulation of cysteine-type endopeptidase activity
(GO:2000117)
Negative regulation of lipopolysaccharide-mediated signaling pathway
(GO:0031665)
Negative regulation of membrane potential
(GO:0045837)
Negative regulation of single-species biofilm formation in or on host organism
(GO:1900229)
Negative regulation of viral genome replication
(GO:0045071)
Negative regulation of viral process
(GO:0048525)
Ossification
(GO:0001503)
Peptidase activity
(GO:0008233)
Plasma membrane
(GO:0005886)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of chondrocyte proliferation
(GO:1902732)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Positive regulation of osteoblast differentiation
(GO:0045669)
Positive regulation of osteoblast proliferation
(GO:0033690)
Positive regulation of protein serine/threonine kinase activity
(GO:0071902)
Positive regulation of toll-like receptor 4 signaling pathway
(GO:0034145)
Protein-containing complex
(GO:0032991)
Protein serine/threonine kinase activator activity
(GO:0043539)
Proteolysis
(GO:0006508)
Recycling endosome
(GO:0055037)
Regulation of cytokine production
(GO:0001817)
Regulation of tumor necrosis factor production
(GO:0032680)
Secretory granule
(GO:0030141)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type peptidase activity
(GO:0008236)
Specific granule
(GO:0042581)

Other Information

Proteins

Lactotransferrin

Genular Protein ID: 2236994172

Symbol: TRFL_MOUSE

Name: Lactotransferrin

UniProtKB Accession Codes:

P08071 P70690 Q61799 Q8CBA0 Q922P2

Database IDs:

Citations:

PubMed ID: 3611056

Title: Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions.

PubMed ID: 3611056

DOI: 10.1016/s0021-9258(18)61088-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1939212

Title: Characterization of estrogen-responsive mouse lactoferrin promoter.

PubMed ID: 1939212

DOI: 10.1016/s0021-9258(18)54719-0

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 707
Mass: 77838
Checksum: E1B32F5FD8748A0F
Sequence:

MRLLIPSLIF LEALGLCLAK ATTVQWCAVS NSEEEKCLRW QNEMRKVGGP PLSCVKKSST 
RQCIQAIVTN RADAMTLDGG TMFDAGKPPY KLRPVAAEVY GTKEQPRTHY YAVAVVKNSS 
NFHLNQLQGL RSCHTGIGRS AGWKIPIGTL RPYLNWNGPP ASLEEAVSKF FSKSCVPGAQ 
KDRFPNLCSS CAGTGANKCA SSPEEPYSGY AGALRCLRDN AGDVAFTRGS TVFEELPNKA 
ERDQYKLLCP DNTWKPVTEY KECHLAQVPS HAVVSRSTND KEEAIWELLR QSQEKFGKKQ 
ASGFQLFASP SGQKDLLFKE SAIGFVRVPQ KVDVGLYLTF SYTTSIQNLN KKQQDVIASK 
ARVTWCAVGS EEKRKCDQWN RASRGRVTCI SFPTTEDCIV AIMKGDADAM SLDGGYIYTA 
GKCGLVPVLA ENQKSSKSNG LDCVNRPVEG YLAVAAVRRE DAGFTWSSLR GKKSCHTAVD 
RTAGWNIPMG LLANQTRSCK FNEFFSQSCA PGADPKSNLC ALCIGDEKGE NKCAPNSKER 
YQGYTGALRC LAEKAGNVAF LKDSTVLQNT DGKNTEEWAR NLKLKDFELL CLDDTRKPVT 
EAKNCHLAIA PNHAVVSRTD KVEVLQQVLL DQQVQFGRNG QRCPGEFCLF QSKTKNLLFN 
DNTECLAKIP GKTTSEKYLG KEYVIATERL KQCSSSPLLE ACAFLTQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ltf

Associated with

Other Information

Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions. PubMed ID: 3611056

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334