Details for: Ly6e

Gene ID: 17069

Symbol: Ly6e

Ensembl ID: ENSMUSG00000022587

Description: lymphocyte antigen 6 family member E

Associated with

Other Information

Genular Protein ID: 4073459505

Symbol: LY6E_MOUSE

Name: Stem cell antigen 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8258699

Title: Isolation of a cDNA encoding thymic shared antigen-1. A new member of the Ly6 family with a possible role in T cell development.

PubMed ID: 8258699

PubMed ID: 8202484

Title: Mouse stem cell antigen Sca-2 is a member of the Ly-6 family of cell surface proteins.

PubMed ID: 8202484

DOI: 10.1073/pnas.91.12.5296

PubMed ID: 8662090

Title: Genomic organization and expression of mouse thymic shared antigen-1 (TSA-1): evidence for a processed pseudogene.

PubMed ID: 8662090

DOI: 10.1007/s002510050115

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2987354

Title: A monoclonal antibody that recognizes an Ly-6-linked antigen inhibits the generation of functionally active T cell subsets.

PubMed ID: 2987354

PubMed ID: 3040423

Title: Selective up-regulation by interferon-gamma of surface molecules of the Ly-6 complex in resting T cells: the Ly-6A/E and TAP antigens are preferentially enhanced.

PubMed ID: 3040423

DOI: 10.1002/eji.1830170816

PubMed ID: 1531995

Title: Thymic shared antigen-1. A novel thymocyte marker discriminating immature from mature thymocyte subsets.

PubMed ID: 1531995

PubMed ID: 7499840

Title: Modulation of TCR-mediated signaling pathway by thymic shared antigen-1 (TSA-1)/stem cell antigen-2 (Sca-2).

PubMed ID: 7499840

PubMed ID: 8642345

Title: Protection from anti-TCR/CD3-induced apoptosis in immature thymocytes by a signal through thymic shared antigen-1/stem cell antigen-2.

PubMed ID: 8642345

DOI: 10.1084/jem.183.5.2355

PubMed ID: 9575182

Title: Physical and functional association between thymic shared antigen-1/stem cell antigen-2 and the T cell receptor complex.

PubMed ID: 9575182

DOI: 10.1074/jbc.273.20.12301

PubMed ID: 11784869

Title: Essential role for the lymphostromal plasma membrane Ly-6 superfamily molecule thymic shared antigen 1 in development of the embryonic adrenal gland.

PubMed ID: 11784869

DOI: 10.1128/mcb.22.3.946-952.2002

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26276394

Title: Mechanisms of inhibition and potentiation of alpha4beta2 nicotinic acetylcholine receptors by members of the Ly6 protein family.

PubMed ID: 26276394

DOI: 10.1074/jbc.m115.647248

PubMed ID: 28679758

Title: A Cell Fusion-Based Screening Method Identifies Glycosylphosphatidylinositol-Anchored Protein Ly6e as the Receptor for Mouse Endogenous Retroviral Envelope Syncytin-A.

PubMed ID: 28679758

DOI: 10.1128/jvi.00832-17

PubMed ID: 29500366

Title: Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice.

PubMed ID: 29500366

DOI: 10.1038/s41598-018-22040-2

PubMed ID: 32704094

Title: LY6E impairs coronavirus fusion and confers immune control of viral disease.

PubMed ID: 32704094

DOI: 10.1038/s41564-020-0769-y

Sequence Information:

  • Length: 136
  • Mass: 14392
  • Checksum: 5A1CBBE1464DC029
  • Sequence:
  • MSATSNMRVF LPVLLAALLG MEQVHSLMCF SCTDQKNNIN CLWPVSCQEK DHYCITLSAA 
    AGFGNVNLGY TLNKGCSPIC PSENVNLNLG VASVNSYCCQ SSFCNFSAAG LGLRASIPLL 
    GLGLLLSLLA LLQLSP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.