Genular: Defining Cellular Identity and Function

Details for: Cd180

Gene ID: 17079

Symbol: Cd180

Ensembl ID: ENSMUSG00000021624

Description: CD180 antigen

Associated with

Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Toll-like receptor cascades
(R-MMU-168898)
Toll like receptor 4 (tlr4) cascade
(R-MMU-166016)
B cell proliferation involved in immune response
(GO:0002322)
Cellular response to lipopolysaccharide
(GO:0071222)
Extracellular matrix
(GO:0031012)
Extracellular space
(GO:0005615)
Immune system process
(GO:0002376)
Inflammatory response
(GO:0006954)
Innate immune response
(GO:0045087)
Lipopolysaccharide-mediated signaling pathway
(GO:0031663)
Membrane
(GO:0016020)
Mitotic spindle
(GO:0072686)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Plasma membrane
(GO:0005886)
Positive regulation of lipopolysaccharide-mediated signaling pathway
(GO:0031666)
Protein binding
(GO:0005515)

Other Information

Proteins

CD180 antigen

Genular Protein ID: 4231855721

Symbol: CD180_MOUSE

Name: CD180 antigen

UniProtKB Accession Codes:

Q62192 Q8C251

Database IDs:

Citations:

PubMed ID: 7897216

Title: RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family.

PubMed ID: 7897216

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 9686597

Title: Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression.

PubMed ID: 9686597

PubMed ID: 10880523

Title: The Toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells.

PubMed ID: 10880523

DOI: 10.1084/jem.192.1.23

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21959264

Title: Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family.

PubMed ID: 21959264

DOI: 10.1016/j.jmb.2011.09.020

Sequence Information:

Length: 661
Mass: 74302
Checksum: 12F91AAB4224602E
Sequence:

MAPDISCFFL VALFLASCRA TTSSDQKCIE KEVNKTYNCE NLGLNEIPGT LPNSTECLEF 
SFNVLPTIQN TTFSRLINLT FLDLTRCQIY WIHEDTFQSQ HRLDTLVLTA NPLIFMAETA 
LSGPKALKHL FFIQTGISSI DFIPLHNQKT LESLYLGSNH ISSIKLPKGF PTEKLKVLDF 
QNNAIHYLSK EDMSSLQQAT NLSLNLNGND IAGIELGAFD SAVFQSLNFG GTQNLLVIFK 
GLKNSTIQSL WLGTFEDMDD EDISPAVFEG LCEMSVESIN LQKHYFFNIS SNTFHCFSGL 
QELDLTATHL SELPSGLVGL STLKKLVLSA NKFENLCQIS ASNFPSLTHL SIKGNTKRLE 
LGTGCLENLE NLRELDLSHD DIETSDCCNL QLRNLSHLQS LNLSYNEPLS LKTEAFKECP 
QLELLDLAFT RLKVKDAQSP FQNLHLLKVL NLSHSLLDIS SEQLFDGLPA LQHLNLQGNH 
FPKGNIQKTN SLQTLGRLEI LVLSFCDLSS IDQHAFTSLK MMNHVDLSHN RLTSSSIEAL 
SHLKGIYLNL ASNRISIILP SLLPILSQQR TINLRQNPLD CTCSNIYFLE WYKENMQKLE 
DTEDTLCENP PLLRGVRLSD VTLSCSMAAV GIFFLIVFLL VFAILLIFAV KYFLRWKYQH 
I

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cd180

Associated with

Other Information

RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. PubMed ID: 7897216

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. PubMed ID: 9686597

The Toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells. PubMed ID: 10880523

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079