Genular: Defining Cellular Identity and Function

Details for: Lyz2

Gene ID: 17105

Symbol: Lyz2

Ensembl ID: ENSMUSG00000069516

Description: lysozyme 2

Associated with

Antimicrobial peptides
(R-MMU-6803157)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Catalytic activity
(GO:0003824)
Defense response to bacterium
(GO:0042742)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to gram-positive bacterium
(GO:0050830)
Endoplasmic reticulum lumen
(GO:0005788)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi cis cisterna
(GO:0000137)
Golgi stack
(GO:0005795)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on glycosyl bonds
(GO:0016798)
Identical protein binding
(GO:0042802)
Killing of cells of another organism
(GO:0031640)
Lysozyme activity
(GO:0003796)
Metabolic process
(GO:0008152)
Microvillus
(GO:0005902)
Rough endoplasmic reticulum lumen
(GO:0048237)
Secretory granule
(GO:0030141)
Trans-golgi network transport vesicle
(GO:0030140)

Other Information

Proteins

Lysozyme C-2

Genular Protein ID: 1262224596

Symbol: LYZ2_MOUSE

Name: Lysozyme C-2

UniProtKB Accession Codes:

P08905 Q3TXG2 Q3U5Q2 Q3U690 Q8VE78

Database IDs:

Citations:

PubMed ID: 3413093

Title: Mouse lysozyme M gene: isolation, characterization, and expression studies.

PubMed ID: 3413093

DOI: 10.1073/pnas.85.17.6232

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12411294

Title: Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan.

PubMed ID: 12411294

DOI: 10.1182/blood-2002-07-2319

PubMed ID: 14617511

Title: Mouse lysozyme M is important in pulmonary host defense against Klebsiella pneumoniae infection.

PubMed ID: 14617511

DOI: 10.1164/rccm.200305-669oc

PubMed ID: 14977423

Title: Comparison of the microbicidal and muramidase activities of mouse lysozyme M and P.

PubMed ID: 14977423

DOI: 10.1042/bj20031810

PubMed ID: 15265906

Title: Mouse lysozyme-M knockout mice reveal how the self-determinant hierarchy shapes the T cell repertoire against this circulating self antigen in wild-type mice.

PubMed ID: 15265906

DOI: 10.4049/jimmunol.173.3.1763

PubMed ID: 16204648

Title: Decreased clearance of Pseudomonas aeruginosa from airways of mice deficient in lysozyme M.

PubMed ID: 16204648

DOI: 10.1189/jlb.0205073

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 12613666

Title: Solution structure and activity of mouse lysozyme M.

PubMed ID: 12613666

DOI: 10.1007/s000180300012

Sequence Information:

Length: 148
Mass: 16689
Checksum: 5C768DDCD8071BAF
Sequence:

MKTLLTLGLL LLSVTAQAKV YERCEFARTL KRNGMAGYYG VSLADWVCLA QHESNYNTRA 
TNYNRGDQST DYGIFQINSR YWCNDGKTPR AVNACGINCS ALLQDDITAA IQCAKRVVRD 
PQGIRAWVAW RAHCQNRDLS QYIRNCGV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lyz2

Associated with

Other Information

Mouse lysozyme M gene: isolation, characterization, and expression studies. PubMed ID: 3413093

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan. PubMed ID: 12411294

Mouse lysozyme M is important in pulmonary host defense against Klebsiella pneumoniae infection. PubMed ID: 14617511

Comparison of the microbicidal and muramidase activities of mouse lysozyme M and P. PubMed ID: 14977423

Mouse lysozyme-M knockout mice reveal how the self-determinant hierarchy shapes the T cell repertoire against this circulating self antigen in wild-type mice. PubMed ID: 15265906

Decreased clearance of Pseudomonas aeruginosa from airways of mice deficient in lysozyme M. PubMed ID: 16204648

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Solution structure and activity of mouse lysozyme M. PubMed ID: 12613666