Details for: Marcks

Gene ID: 17118

Symbol: Marcks

Ensembl ID: ENSMUSG00000069662

Description: myristoylated alanine rich protein kinase C substrate

Associated with

Other Information

Genular Protein ID: 2932822053

Symbol: MARCS_MOUSE

Name: Myristoylated alanine-rich C-kinase substrate

UniProtKB Accession Codes:

P26645

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CPTAC 1 CTD 1 ChiTaRS 1 DNASU 1 DisProt 1 EMBL 2 EPD 1 Ensembl 1 EvolutionaryTrace 1 GO 41 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SAM 1 STRING 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 2006186

Title: Cloning and molecular characterization of the murine macrophage '68-kDa' protein kinase C substrate and its regulation by bacterial lipopolysaccharide.

PubMed ID: 2006186

DOI: 10.1073/pnas.88.6.2505

PubMed ID: 1868832

Title: Protein kinase C activation potently down-regulates the expression of its major substrate, 80K, in Swiss 3T3 cells.

PubMed ID: 1868832

DOI: 10.1002/j.1460-2075.1991.tb07789.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2384168

Title: Purification and internal amino acid sequence of the 80 kDa protein kinase C substrate from Swiss 3T3 fibroblasts. Homology with substrates from brain.

PubMed ID: 2384168

DOI: 10.1016/0014-5793(90)81030-r

PubMed ID: 8849678

Title: p42 MAPK phosphorylates 80 kDa MARCKS at Ser-113.

PubMed ID: 8849678

DOI: 10.1016/0014-5793(96)00991-x

PubMed ID: 1396720

Title: Relationship between the major protein kinase C substrates acidic 80-kDa protein-kinase-C substrate (80K) and myristoylated alanine-rich C-kinase substrate (MARCKS). Members of a gene family or equivalent genes in different species.

PubMed ID: 1396720

DOI: 10.1111/j.1432-1033.1992.tb17255.x

PubMed ID: 7588787

Title: The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C.

PubMed ID: 7588787

DOI: 10.1111/j.1432-1033.1995.448_2.x

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 12577052

Title: Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca2+-calmodulin.

PubMed ID: 12577052

DOI: 10.1038/nsb900

Sequence Information:

  • Length: 309
  • Mass: 29661
  • Checksum: 3BB1E392D74B5A98
  • Sequence:
    • MGAQFSKTAA KGEATAERPG EAAVASSPSK ANGQENGHVK VNGDASPAAA EPGAKEELQA 
NGSAPAADKE EPASGSAATP AAAEKDEAAA ATEPGAGAAD KEAAEAEPAE PSSPAAEAEG 
ASASSTSSPK AEDGAAPSPS SETPKKKKKR FSFKKSFKLS GFSFKKSKKE SGEGAEAEGA 
TAEGAKDEAA AAAGGEGAAA PGEQAGGAGA EGAAGGEPRE AEAAEPEQPE QPEQPAAEEP 
QAEEQSEAAG EKAEEPAPGA TAGDASSAAG PEQEAPAATD EAAASAAPAA SPEPQPECSP 
EAPPAPTAE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.