Genular: Defining Cellular Identity and Function

Details for: Mad1l1

Gene ID: 17120

Symbol: Mad1l1

Ensembl ID: ENSMUSG00000029554

Description: MAD1 mitotic arrest deficient 1-like 1

Associated with

Amplification of signal from the kinetochores
(R-MMU-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-MMU-141444)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Eml4 and nudc in mitotic spindle formation
(R-MMU-9648025)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Separation of sister chromatids
(R-MMU-2467813)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Attachment of mitotic spindle microtubules to kinetochore
(GO:0051315)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Cytoplasm
(GO:0005737)
Cytoplasmic sequestering of protein
(GO:0051220)
Cytoskeleton
(GO:0005856)
Deactivation of mitotic spindle assembly checkpoint
(GO:1902426)
Identical protein binding
(GO:0042802)
Kinetochore
(GO:0000776)
Kinetochore binding
(GO:0043515)
Mad1 complex
(GO:1990706)
Mitotic spindle
(GO:0072686)
Mitotic spindle assembly checkpoint mad1-mad2 complex
(GO:1990728)
Mitotic spindle assembly checkpoint signaling
(GO:0007094)
Mitotic spindle pole
(GO:0097431)
Negative regulation of t cell proliferation
(GO:0042130)
Nuclear envelope
(GO:0005635)
Nuclear pore nuclear basket
(GO:0044615)
Nucleus
(GO:0005634)
Positive regulation of mitotic cell cycle spindle assembly checkpoint
(GO:0090267)
Protein binding
(GO:0005515)
Regulation of metaphase plate congression
(GO:0090235)
Regulation of mitotic cell cycle phase transition
(GO:1901990)
Spindle pole
(GO:0000922)
Thymus development
(GO:0048538)

Other Information

Proteins

Mitotic spindle assembly checkpoint protein MAD1

Genular Protein ID: 3930034085

Symbol: MD1L1_MOUSE

Name: Mitotic spindle assembly checkpoint protein MAD1

UniProtKB Accession Codes:

Q9WTX8 Q9WTX9

Database IDs:

Citations:

PubMed ID: 10049595

Title: Mitotic checkpoint locus MAD1L1 maps to human chromosome 7p22 and mouse chromosome 5.

PubMed ID: 10049595

DOI: 10.1006/geno.1998.5654

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 717
Mass: 83541
Checksum: 4EEB880AE7D80838
Sequence:

MEDLGENTTV LSSLRSLNNF ISQRMEGTSG LDVSTSASGS LQKQYEYHMQ LEERAEQIRS 
KSYLIQVERE KMQMELSHKR ARVELERAAS TNARNYEREV DRNQELLARI RQLQECEATA 
EEKMREQLER HRLCKQNLDA VSQQLREQED SLASAREMIS SLKGRVSELQ LSAMDQKVQV 
KRLESEKQEL KEQLELQQRK WQEANQKIQE LQASQDERAE HEQKIKDLEQ KLCLQEQDAA 
VVKSMKSELM RMPRMERELK RLHEENTHLR EMKETNGLLT EELEGLQRKL SRQEKMQEAL 
VDLELEKEKL LAKLQSWENL DQTMGLNLRT PEDLSRFVVE LQQRELTLKE KNNSITSSAR 
GLEKVQQQLQ DEVRQANAQL LEERKKRETH EALARRLQKR NALLTKERDG MRAILGSYDS 
ELTQTEYSTQ LTQRLWEAED MVQKVHAHSS EMEAQLSQAL EELGVQKQRA DTLEMELKML 
KAQTSSAESS FSFCKEEVDA LRLKVEELEG ERSRLEQEKQ VLEMQMEKLT LQGDYNQSRT 
KVLHMSLNPI SMARQRQHED HDRLQEECER LRGLVHALER GGPIPADLEA ASSLPSSKEV 
AELRKQVESA ELKNQRLKEV FQTKIQEFRK VCYTLTGYQI DVTTESQYRL TSRYAEHQTD 
CLIFKATGPS GSKMQLLETE FSRSVPELIE LHLLQQDSIP AFLSALTIEL FSRQTSI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.