Details for: Mxd3

Gene ID: 17121

Symbol: Mxd3

Ensembl ID: ENSMUSG00000021485

Description: Max dimerization protein 3

Associated with

  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Protein dimerization activity
    (GO:0046983)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)

Other Information

Genular Protein ID: 2404124062

Symbol: MAD3_MOUSE

Name: Max dimerization protein 3

UniProtKB Accession Codes:

Q80US8 Q60947

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DIP 1 DNASU 1 EMBL 3 EPD 1 Ensembl 1 GO 7 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 8521822

Title: Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.

PubMed ID: 8521822

DOI: 10.1002/j.1460-2075.1995.tb00252.x

PubMed ID: 8617250

Title:

PubMed ID: 8617250

DOI: 10.1002/j.1460-2075.1996.tb00555.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11154258

Title: Targeted deletion of the S-phase-specific Myc antagonist Mad3 sensitizes neuronal and lymphoid cells to radiation-induced apoptosis.

PubMed ID: 11154258

DOI: 10.1128/mcb.21.3.703-712.2001

PubMed ID: 10597267

Title: Mmip-2, a novel RING finger protein that interacts with mad members of the Myc oncoprotein network.

PubMed ID: 10597267

DOI: 10.1038/sj.onc.1203097

Sequence Information:

  • Length: 206
  • Mass: 23635
  • Checksum: 17E1149064907085
  • Sequence:
    • MEPVASNIQV LLQAAEFLER REREAEHGYA SLCPHHSPGT VCRRRKPPLQ APGALNSGRS 
VHNELEKRRR AQLKRCLEQL RQQMPLGVDC TRYTTLSLLR RARVHIQKLE EQEQQARRLK 
EKLRSKQQSL QQQLEQLQGL PGARERERLR ADSLDSSGLS SERSDSDQED LEVDVESLVF 
GTETELLQSF SAGREHSYSH STCAWL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.