Genular: Defining Cellular Identity and Function

Details for: Man2a1

Gene ID: 17158

Symbol: Man2a1

Ensembl ID: ENSMUSG00000024085

Description: mannosidase 2, alpha 1

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Metabolism of proteins
(R-MMU-392499)
N-glycan antennae elongation in the medial/trans-golgi
(R-MMU-975576)
Post-translational protein modification
(R-MMU-597592)
Reactions specific to the complex n-glycan synthesis pathway
(R-MMU-975578)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Alpha-mannosidase activity
(GO:0004559)
Carbohydrate binding
(GO:0030246)
Carbohydrate metabolic process
(GO:0005975)
Catalytic activity
(GO:0003824)
Cis-golgi network
(GO:0005801)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Golgi medial cisterna
(GO:0005797)
Golgi membrane
(GO:0000139)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on glycosyl bonds
(GO:0016798)
Hydrolase activity, hydrolyzing n-glycosyl compounds
(GO:0016799)
Identical protein binding
(GO:0042802)
In utero embryonic development
(GO:0001701)
Liver development
(GO:0001889)
Lung alveolus development
(GO:0048286)
Mannose metabolic process
(GO:0006013)
Mannosidase activity
(GO:0015923)
Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
(GO:0004572)
Membrane
(GO:0016020)
Metabolic process
(GO:0008152)
Metal ion binding
(GO:0046872)
Mitochondrion organization
(GO:0007005)
N-glycan processing
(GO:0006491)
Positive regulation of neurogenesis
(GO:0050769)
Protein deglycosylation
(GO:0006517)
Protein homodimerization activity
(GO:0042803)
Respiratory gaseous exchange by respiratory system
(GO:0007585)
Retina morphogenesis in camera-type eye
(GO:0060042)
Vacuole organization
(GO:0007033)

Other Information

Proteins

Alpha-mannosidase 2
Q8C4L1_MOUSE

Genular Protein ID: 633104602

Symbol: MA2A1_MOUSE

Name: Alpha-mannosidase 2

UniProtKB Accession Codes:

P27046 B9EHS6

Database IDs:

Citations:

PubMed ID: 1757461

Title: Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans.

PubMed ID: 1757461

DOI: 10.1083/jcb.115.6.1521

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1150
Mass: 131631
Checksum: 5CDD9DD388DF5BC6
Sequence:

MKLSRQFTVF GSAIFCVVIF SLYLMLDRGH LDYPRGPRQE GSFPQGQLSI LQEKIDHLER 
LLAENNEIIS NIRDSVINLS ESVEDGPRGS PGNASQGSIH LHSPQLALQA DPRDCLFASQ 
SGSQPRDVQM LDVYDLIPFD NPDGGVWKQG FDIKYEADEW DHEPLQVFVV PHSHNDPGWL 
KTFNDYFRDK TQYIFNNMVL KLKEDSSRKF MWSEISYLAK WWDIIDIPKK EAVKSLLQNG 
QLEIVTGGWV MPDEATPHYF ALIDQLIEGH QWLEKNLGVK PRSGWAIDPF GHSPTMAYLL 
KRAGFSHMLI QRVHYAIKKH FSLHKTLEFF WRQNWDLGSA TDILCHMMPF YSYDIPHTCG 
PDPKICCQFD FKRLPGGRYG CPWGVPPEAI SPGNVQSRAQ MLLDQYRKKS KLFRTKVLLA 
PLGDDFRFSE YTEWDLQCRN YEQLFSYMNS QPHLKVKIQF GTLSDYFDAL EKAVAAEKKS 
SQSVFPALSG DFFTYADRDD HYWSGYFTSR PFYKRMDRIM ESRIRAAEIL YQLALKQAQK 
YKINKFLSSP HYTTLTEARR NLGLFQHHDA ITGTAKDWVV VDYGTRLFQS LNSLEKIIGD 
SAFLLILKDK KLYQSDPSKA FLEMDTKQSS QDSLPQKIII QLSAQEPRYL VVYNPFEQER 
HSVVSIRVNS ATVKVLSDSG KPVEVQVSAV WNDMRTISQA AYEVSFLAHI PPLGLKVFKI 
LESQSSSSHL ADYVLYNNDG LAENGIFHVK NMVDAGDAIT IENPFLAIWF DRSGLMEKVR 
RKEDSRQHEL KVQFLWYGTT NKRDKSGAYL FLPDGQGQPY VSLRPPFVRV TRGRIYSDVT 
CFLEHVTHKV RLYNIQGIEG QSMEVSNIVN IRNVHNREIV MRISSKINNQ NRYYTDLNGY 
QIQPRRTMSK LPLQANVYPM CTMAYIQDAE HRLTLLSAQS LGASSMASGQ IEVFMDRRLM 
QDDNRGLGQG VHDNKITANL FRILLEKRSA VNMEEEKKSP VSYPSLLSHM TSSFLNHPFL 
PMVLSGQLPS PAFELLSEFP LLQSSLPCDI HLVNLRTIQS KMGKGYSDEA ALILHRKGFD 
CQFSSRGIGL PCSTTQGKMS VLKLFNKFAV ESLVPSSLSL MHSPPDAQNM SEVSLSPMEI 
STFRIRLRWT

Genular Protein ID: 2683939687

Symbol: Q8C4L1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8C4L1

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 68
Mass: 7489
Checksum: 1B705BBF3F0AC566
Sequence:

FSSRGIGLPC STTQGKMSVL KLFNKFAGES LVPSSLSLMH SPPDAQNMSE VSLSPMEIST 
FRIRLRWT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Man2a1

Associated with

Other Information

Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans. PubMed ID: 1757461

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073