Genular: Defining Cellular Identity and Function

Details for: Masp2

Gene ID: 17175

Symbol: Masp2

Ensembl ID: ENSMUSG00000028979

Description: MBL associated serine protease 2

Associated with

Complement cascade
(R-MMU-166658)
Creation of c4 and c2 activators
(R-MMU-166786)
Ficolins bind to repetitive carbohydrate structures on the target cell surface
(R-MMU-2855086)
Immune system
(R-MMU-168256)
Initial triggering of complement
(R-MMU-166663)
Innate immune system
(R-MMU-168249)
Lectin pathway of complement activation
(R-MMU-166662)
Calcium-dependent protein binding
(GO:0048306)
Calcium ion binding
(GO:0005509)
Complement activation
(GO:0006956)
Complement activation, classical pathway
(GO:0006958)
Complement activation, lectin pathway
(GO:0001867)
Complement component c4b binding
(GO:0001855)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Metal ion binding
(GO:0046872)
Peptidase activity
(GO:0008233)
Proteolysis
(GO:0006508)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type peptidase activity
(GO:0008236)

Other Information

Proteins

Mannan-binding lectin serine protease 2

Genular Protein ID: 4117899873

Symbol: MASP2_MOUSE

Name: Mannan-binding lectin serine protease 2

UniProtKB Accession Codes:

Q91WP0 B1ARY2 B1ARY3 Q9QXA4 Q9QXD2 Q9QXD5 Q9Z338

Database IDs:

Citations:

PubMed ID: 9794427

Title: Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebrates.

PubMed ID: 9794427

PubMed ID: 10586086

Title: The rat and mouse homologues of MASP-2 and MAp19, components of the mannan-binding lectin activation pathway of complement.

PubMed ID: 10586086

PubMed ID: 15672593

Title: Organization of the MASP2 locus and its expression profile in mouse and rat.

PubMed ID: 15672593

DOI: 10.1007/s00335-004-3006-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16944957

Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PubMed ID: 16944957

DOI: 10.1021/pr060186m

Sequence Information:

Length: 685
Mass: 75517
Checksum: F56A6D522BC7099D
Sequence:

MRLLIFLGLL WSLVATLLGS KWPEPVFGRL VSPGFPEKYA DHQDRSWTLT APPGYRLRLY 
FTHFDLELSY RCEYDFVKLS SGTKVLATLC GQESTDTEQA PGNDTFYSLG PSLKVTFHSD 
YSNEKPFTGF EAFYAAEDVD ECRVSLGDSV PCDHYCHNYL GGYYCSCRAG YVLHQNKHTC 
SALCSGQVFT GRSGYLSSPE YPQPYPKLSS CTYSIRLEDG FSVILDFVES FDVETHPEAQ 
CPYDSLKIQT DKGEHGPFCG KTLPPRIETD SHKVTITFAT DESGNHTGWK IHYTSTARPC 
PDPTAPPNGS ISPVQAIYVL KDRFSVFCKT GFELLQGSVP LKSFTAVCQK DGSWDRPMPE 
CSIIDCGPPD DLPNGHVDYI TGPEVTTYKA VIQYSCEETF YTMSSNGKYV CEADGFWTSS 
KGEKLPPVCE PVCGLSTHTI GGRIVGGQPA KPGDFPWQVL LLGQTTAAAG ALIHDNWVLT 
AAHAVYEKRM AASSLNIRMG ILKRLSPHYT QAWPEEIFIH EGYTHGAGFD NDIALIKLKN 
KVTINGSIMP VCLPRKEAAS LMRTDFTGTV AGWGLTQKGL LARNLMFVDI PIADHQKCTA 
VYEKLYPGVR VSANMLCAGL ETGGKDSCRG DSGGALVFLD NETQRWFVGG IVSWGSINCG 
AADQYGVYTK VINYIPWIEN IISNF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Masp2

Associated with

Other Information

Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebrates. PubMed ID: 9794427

The rat and mouse homologues of MASP-2 and MAp19, components of the mannan-binding lectin activation pathway of complement. PubMed ID: 10586086

Organization of the MASP2 locus and its expression profile in mouse and rat. PubMed ID: 15672593

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Proteome-wide characterization of N-glycosylation events by diagonal chromatography. PubMed ID: 16944957