Genular: Defining Cellular Identity and Function

Details for: Mbd1

Gene ID: 17190

Symbol: Mbd1

Ensembl ID: ENSMUSG00000024561

Description: methyl-CpG binding domain protein 1

Associated with

Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of transcription cofactors
(R-MMU-3899300)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Chromosome
(GO:0005694)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Double-stranded methylated dna binding
(GO:0010385)
Heterochromatin
(GO:0000792)
Intracellular membrane-bounded organelle
(GO:0043231)
Metal ion binding
(GO:0046872)
Methyl-cpg binding
(GO:0008327)
Negative regulation of astrocyte differentiation
(GO:0048712)
Negative regulation of gene expression
(GO:0010629)
Nuclear matrix
(GO:0016363)
Nuclear speck
(GO:0016607)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Unmethylated cpg binding
(GO:0045322)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Methyl-CpG-binding protein MBD1
A0A0R4J159_MOUSE

Genular Protein ID: 2442231604

Symbol: MBD1_MOUSE

Name: Methyl-CpG-binding protein MBD1

UniProtKB Accession Codes:

Q9Z2E2 Q3TMA4 Q3U101 Q6NSW0 Q792D6 Q8CCL9 Q9DC19

Database IDs:

Citations:

PubMed ID: 9774669

Title: Identification and characterization of a family of mammalian methyl-CpG binding proteins.

PubMed ID: 9774669

DOI: 10.1128/mcb.18.11.6538

PubMed ID: 10441743

Title: Genomic structure and chromosomal mapping of the murine and human mbd1, mbd2, mbd3, and mbd4 genes.

PubMed ID: 10441743

DOI: 10.1007/s003359901112

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12697822

Title: The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1.

PubMed ID: 12697822

DOI: 10.1128/mcb.23.9.3226-3236.2003

PubMed ID: 15060159

Title: Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains.

PubMed ID: 15060159

DOI: 10.1128/mcb.24.8.3387-3395.2004

PubMed ID: 15777793

Title: The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix.

PubMed ID: 15777793

DOI: 10.1016/j.yexcr.2004.12.020

Sequence Information:

Length: 636
Mass: 70023
Checksum: 02D8B94EBD522F65
Sequence:

MAESWQDCPA LGPGWKRRES FRKSGASFGR SDIYYQSPTG EKIRSKVELT RYLGPACDLT 
LFDFRQGTLC HPIPKTHPLA VPSKKKKKPS KPAKTKKQQV GLQRSEVRIE TPQGEYKAPT 
ATALASLSVS ASASSSASAS ASASSHAPVC CENCGIHFSW DGVKRQRLKT LCKDCRAQRI 
AFNREQRMFK RVGCGDCAAC LVKEDCGVCS TCRLQLPSDV ASGLYCKCER RRCLRIMEKS 
RGCGVCRGCQ TQEDCGHCCI CLRSPRPGLK RQWRCLQRRC FWGKRDSSKR GSKVASQRHS 
QAPPLPPHPA SQYTEPTELH ISDIAPTSPA EFIYYCVDED EDELQPYTNQ RQNRKCGACA 
ACLRRMDCGR CDFCCDKPKF GGGNQKRQKC RWRQCLQFAM KRLLPSAGSG SGEGAGLRPY 
QTHQTHQKRP ASARQLQLSS PLKAPWAVVT APPGPVRDSR KQQAGRGSVL PQPDTDFVFL 
QEGTSSAMQM PGTAAASTEV PVQAAQCSAP SWVVALPQVK QETADAPEEW TAVTTFLTSS 
TLQSGFPSKA ADPDLSPVKQ EPPGPEEDGE EKKDDVSETT PAEEIGGVGT PVITEIFSLG 
GTRLRDAEAW LPRLHKLLAV NEKEYFTELQ LKEEVL

Genular Protein ID: 3530048908

Symbol: A0A0R4J159_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0R4J159

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 588
Mass: 64183
Checksum: 00AD7484FC204195
Sequence:

MAESWQDCPA LGPGWKRRES FRKSGASFGR SDIYYQSPTG EKIRSKVELT RYLGPACDLT 
LFDFRQGTLC HPIPKTHPLA VPSKKKKKPS KPAKTKKQQV GLQRSEVRRE TPQGEYKAPT 
ATALASLSVS ASASSSASAS ASSSASASAS ASSHAPVCCE NCGIHFSWDG VKRQRLKTLC 
KDCRAQRIAF NREQRMFKRV GCGDCAACLV KEDCGVCSTC RLQLPSDVAS GLYCKCERRR 
CLRIMEKSRG CGVCRGCQTQ EDCGHCCICL RSPRPGLKRQ WRCLQRRCFW GKRDSSKRGS 
KVASQRHSQA PPLPPHPASQ YTEPTELHIS DIAPTSPAEF IYYCVDEDED ELKRLLPSAG 
SGSGEGAGLR PYQTHQTHQK RPASARQLQL SSPLKAPWAV VTAPPGPVRD SRKQQAGRGS 
VLPQPDTDFV FLQEGTSSAM QMPGTAAACT EVPVQAAQCS APSWVVALPQ VKQETADAPE 
EWTAVTTFLT SSTLQSGFPS KAADPDLSPV KQEPPGPEED GEEKKDDVSE TTPAEEIGGV 
GTPVITEIFS LGGTRLRDAE AWLPRLHKLL AVNEKEYFTE LQLKEEVL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mbd1

Associated with

Other Information

Identification and characterization of a family of mammalian methyl-CpG binding proteins. PubMed ID: 9774669

Genomic structure and chromosomal mapping of the murine and human mbd1, mbd2, mbd3, and mbd4 genes. PubMed ID: 10441743

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. PubMed ID: 12697822

Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains. PubMed ID: 15060159

The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. PubMed ID: 15777793

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303