Genular: Defining Cellular Identity and Function

Details for: Mbl1

Gene ID: 17194

Symbol: Mbl1

Ensembl ID: ENSMUSG00000037780

Description: mannose-binding lectin (protein A) 1

Associated with

Calcium-dependent carbohydrate binding
(GO:0120153)
Calcium-dependent protein binding
(GO:0048306)
Calcium ion binding
(GO:0005509)
Carbohydrate binding
(GO:0030246)
Collagen trimer
(GO:0005581)
Complement activation, classical pathway
(GO:0006958)
Complement activation, lectin pathway
(GO:0001867)
Defense response to gram-positive bacterium
(GO:0050830)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Killing by host of symbiont cells
(GO:0051873)
Mannose binding
(GO:0005537)
Metal ion binding
(GO:0046872)
Multivesicular body
(GO:0005771)
Oligosaccharide binding
(GO:0070492)
Phosphatidylinositol-4-phosphate binding
(GO:0070273)
Polysaccharide binding
(GO:0030247)
Positive regulation of phagocytosis
(GO:0050766)
Protease binding
(GO:0002020)
Protein homodimerization activity
(GO:0042803)
Protein homotrimerization
(GO:0070207)
Surfactant homeostasis
(GO:0043129)

Other Information

Proteins

Mannose-binding protein A

Genular Protein ID: 3003397525

Symbol: MBL1_MOUSE

Name: Mannose-binding protein A

UniProtKB Accession Codes:

P39039 Q0P6H1

Database IDs:

Citations:

PubMed ID: 1712818

Title: Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant.

PubMed ID: 1712818

PubMed ID: 1637828

Title: cDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: similarity to mannose-binding proteins.

PubMed ID: 1637828

DOI: 10.1021/bi00145a012

PubMed ID: 7766991

Title: Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes.

PubMed ID: 7766991

DOI: 10.1007/bf00303252

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25419660

Title: Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin.

PubMed ID: 25419660

DOI: 10.1371/journal.pone.0113498

Sequence Information:

Length: 239
Mass: 25396
Checksum: D222F1A748D424D9
Sequence:

MLLLPLLPVL LCVVSVSSSG SQTCEDTLKT CSVIACGRDG RDGPKGEKGE PGQGLRGLQG 
PPGKLGPPGS VGSPGSPGPK GQKGDHGDNR AIEEKLANME AEIRILKSKL QLTNKLHAFS 
MGKKSGKKLF VTNHEKMPFS KVKSLCTELQ GTVAIPRNAE ENKAIQEVAT GIAFLGITDE 
ATEGQFMYVT GGRLTYSNWK KDEPNNHGSG EDCVIILDNG LWNDISCQAS FKAVCEFPA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mbl1

Associated with

Other Information

Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant. PubMed ID: 1712818

cDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: similarity to mannose-binding proteins. PubMed ID: 1637828

Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes. PubMed ID: 7766991

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079