Genular: Defining Cellular Identity and Function

Details for: Mbl2

Gene ID: 17195

Symbol: Mbl2

Ensembl ID: ENSMUSG00000024863

Description: mannose-binding lectin (protein C) 2

Associated with

Complement cascade
(R-MMU-166658)
Creation of c4 and c2 activators
(R-MMU-166786)
Immune system
(R-MMU-168256)
Initial triggering of complement
(R-MMU-166663)
Innate immune system
(R-MMU-168249)
Lectin pathway of complement activation
(R-MMU-166662)
Antiviral innate immune response
(GO:0140374)
Calcium-dependent protein binding
(GO:0048306)
Calcium ion binding
(GO:0005509)
Carbohydrate binding
(GO:0030246)
Cell surface pattern recognition receptor signaling pathway
(GO:0002752)
Collagen trimer
(GO:0005581)
Complement activation, classical pathway
(GO:0006958)
Complement activation, lectin pathway
(GO:0001867)
Defense response to gram-positive bacterium
(GO:0050830)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Galactose binding
(GO:0005534)
Identical protein binding
(GO:0042802)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Killing by host of symbiont cells
(GO:0051873)
Mannose binding
(GO:0005537)
Multivesicular body
(GO:0005771)
Negative regulation of viral process
(GO:0048525)
Phosphatidylinositol-4-phosphate binding
(GO:0070273)
Positive regulation of complement activation
(GO:0045917)
Positive regulation of opsonization
(GO:1903028)
Positive regulation of phagocytosis
(GO:0050766)
Positive regulation of protein processing
(GO:0010954)
Protease binding
(GO:0002020)
Protein-containing complex
(GO:0032991)
Protein self-association
(GO:0043621)
Proteolysis
(GO:0006508)
Serine-type endopeptidase complex
(GO:1905370)
Signaling receptor binding
(GO:0005102)
Surfactant homeostasis
(GO:0043129)

Other Information

Proteins

Mannose-binding protein C

Genular Protein ID: 1779764348

Symbol: MBL2_MOUSE

Name: Mannose-binding protein C

UniProtKB Accession Codes:

P41317

Database IDs:

Citations:

PubMed ID: 1712818

Title: Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant.

PubMed ID: 1712818

PubMed ID: 7766991

Title: Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes.

PubMed ID: 7766991

DOI: 10.1007/bf00303252

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 244
Mass: 25957
Checksum: 49AE84E2290DEB0A
Sequence:

MSIFTSFLLL CVVTVVYAET LTEGVQNSCP VVTCSSPGLN GFPGKDGRDG AKGEKGEPGQ 
GLRGLQGPPG KVGPTGPPGN PGLKGAVGPK GDRGDRAEFD TSEIDSEIAA LRSELRALRN 
WVLFSLSEKV GKKYFVSSVK KMSLDRVKAL CSEFQGSVAT PRNAEENSAI QKVAKDIAYL 
GITDVRVEGS FEDLTGNRVR YTNWNDGEPN NTGDGEDCVV ILGNGKWNDV PCSDSFLAIC 
EFSD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mbl2

Associated with

Other Information

Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant. PubMed ID: 1712818

Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes. PubMed ID: 7766991

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 1712818

PubMed ID: 7766991

PubMed ID: 15489334

PubMed ID: 21183079