Genular: Defining Cellular Identity and Function

Details for: Mc1r

Gene ID: 17199

Symbol: Mc1r

Ensembl ID: ENSMUSG00000074037

Description: melanocortin 1 receptor

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Cytoplasm
(GO:0005737)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Intracellular signal transduction
(GO:0035556)
Melanin biosynthetic process
(GO:0042438)
Melanocortin receptor activity
(GO:0004977)
Melanocyte-stimulating hormone receptor activity
(GO:0004980)
Membrane
(GO:0016020)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Pigmentation
(GO:0043473)
Plasma membrane
(GO:0005886)
Positive regulation of protein kinase a signaling
(GO:0010739)
Positive regulation of protein kinase c signaling
(GO:0090037)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of metabolic process
(GO:0019222)
Sensory perception of pain
(GO:0019233)
Signal transduction
(GO:0007165)
Ubiquitin protein ligase binding
(GO:0031625)
Uv-damage excision repair
(GO:0070914)

Other Information

Proteins

Melanocyte-stimulating hormone receptor

Genular Protein ID: 1088909475

Symbol: MSHR_MOUSE

Name: Melanocyte-stimulating hormone receptor

UniProtKB Accession Codes:

Q01727 Q75NA3

Database IDs:

Citations:

PubMed ID: 1325670

Title: The cloning of a family of genes that encode the melanocortin receptors.

PubMed ID: 1325670

DOI: 10.1126/science.1325670

PubMed ID: 15653560

Title: A nucleotide substitution responsible for the tawny coat color mutation carried by the MSKR inbred strain of mice.

PubMed ID: 15653560

DOI: 10.1093/jhered/esi022

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 315
Mass: 35226
Checksum: 9240C7D02B336235
Sequence:

MSTQEPQKSL LGSLNSNATS HLGLATNQSE PWCLYVSIPD GLFLSLGLVS LVENVLVVIA 
ITKNRNLHSP MYYFICCLAL SDLMVSVSIV LETTIILLLE AGILVARVAL VQQLDNLIDV 
LICGSMVSSL CFLGIIAIDR YISIFYALRY HSIVTLPRAR RAVVGIWMVS IVSSTLFITY 
YKHTAVLLCL VTFFLAMLAL MAILYAHMFT RACQHAQGIA QLHKRRRSIR QGFCLKGAAT 
LTILLGIFFL CWGPFFLHLL LIVLCPQHPT CSCIFKNFNL FLLLIVLSST VDPLIYAFRS 
QELRMTLKEV LLCSW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.