Genular: Defining Cellular Identity and Function

Details for: Mc4r

Gene ID: 17202

Symbol: Mc4r

Ensembl ID: ENSMUSG00000047259

Description: melanocortin 4 receptor

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Cytoplasm
(GO:0005737)
Diet induced thermogenesis
(GO:0002024)
Energy reserve metabolic process
(GO:0006112)
Feeding behavior
(GO:0007631)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone binding
(GO:0042562)
Insulin secretion
(GO:0030073)
Melanocortin receptor activity
(GO:0004977)
Melanocyte-stimulating hormone receptor activity
(GO:0004980)
Membrane
(GO:0016020)
Negative regulation of feeding behavior
(GO:2000252)
Neuropeptide binding
(GO:0042923)
Peptide hormone binding
(GO:0017046)
Plasma membrane
(GO:0005886)
Positive regulation of bone resorption
(GO:0045780)
Protein binding
(GO:0005515)
Regulation of eating behavior
(GO:1903998)
Regulation of feeding behavior
(GO:0060259)
Regulation of grooming behavior
(GO:2000821)
Regulation of metabolic process
(GO:0019222)
Response to insulin
(GO:0032868)
Response to melanocyte-stimulating hormone
(GO:1990680)
Signal transduction
(GO:0007165)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Melanocortin receptor 4

Genular Protein ID: 1950898685

Symbol: MC4R_MOUSE

Name: Melanocortin receptor 4

UniProtKB Accession Codes:

P56450 Q49NR4 Q9EQM7

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14531729

Title: Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein.

PubMed ID: 14531729

DOI: 10.1042/bj20031241

PubMed ID: 23869016

Title: Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.

PubMed ID: 23869016

DOI: 10.1126/science.1233000

Sequence Information:

Length: 332
Mass: 36959
Checksum: BAD7018E30CF4FC1
Sequence:

MNSTHHHGMY TSLHLWNRSS YGLHGNASES LGKGHPDGGC YEQLFVSPEV FVTLGVISLL 
ENILVIVAIA KNKNLHSPMY FFICSLAVAD MLVSVSNGSE TIVITLLNST DTDAQSFTVN 
IDNVIDSVIC SSLLASICSL LSIAVDRYFT IFYALQYHNI MTVRRVGIII SCIWAACTVS 
GVLFIIYSDS SAVIICLISM FFTMLVLMAS LYVHMFLMAR LHIKRIAVLP GTGTIRQGTN 
MKGAITLTIL IGVFVVCWAP FFLHLLFYIS CPQNPYCVCF MSHFNLYLIL IMCNAVIDPL 
IYALRSQELR KTFKEIICFY PLGGICELSS RY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mc4r

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. PubMed ID: 14531729

Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. PubMed ID: 23869016

Database document:

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 14531729

PubMed ID: 23869016