Genular: Defining Cellular Identity and Function

Details for: Mcm3

Gene ID: 17215

Symbol: Mcm3

Ensembl ID: ENSMUSG00000041859

Description: minichromosome maintenance complex component 3

Associated with

Activation of atr in response to replication stress
(R-MMU-176187)
Activation of the pre-replicative complex
(R-MMU-68962)
Assembly of the pre-replicative complex
(R-MMU-68867)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Dna replication pre-initiation
(R-MMU-69002)
G1/s transition
(R-MMU-69206)
G2/m checkpoints
(R-MMU-69481)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Orc1 removal from chromatin
(R-MMU-68949)
S phase
(R-MMU-69242)
Switching of origins to a post-replicative state
(R-MMU-69052)
Synthesis of dna
(R-MMU-69239)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cell cycle
(GO:0007049)
Centrosome
(GO:0005813)
Chromosome
(GO:0005694)
Cmg complex
(GO:0071162)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Dna duplex unwinding
(GO:0032508)
Dna replication
(GO:0006260)
Dna replication initiation
(GO:0006270)
Dna strand elongation involved in dna replication
(GO:0006271)
Dna unwinding involved in dna replication
(GO:0006268)
Double-strand break repair via break-induced replication
(GO:0000727)
Helicase activity
(GO:0004386)
Hydrolase activity
(GO:0016787)
Mcm complex
(GO:0042555)
Mitotic dna replication initiation
(GO:1902975)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Premeiotic dna replication
(GO:0006279)
Single-stranded dna binding
(GO:0003697)
Single-stranded dna helicase activity
(GO:0017116)

Other Information

Proteins

DNA replication licensing factor MCM3

Genular Protein ID: 2719939641

Symbol: MCM3_MOUSE

Name: DNA replication licensing factor MCM3

UniProtKB Accession Codes:

P25206 Q61492

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1549468

Title: Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein.

PubMed ID: 1549468

DOI: 10.1093/nar/20.5.1069

PubMed ID: 7925275

Title: DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

PubMed ID: 7925275

DOI: 10.1002/j.1460-2075.1994.tb06751.x

PubMed ID: 10733502

Title: A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication.

PubMed ID: 10733502

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 812
Mass: 91546
Checksum: 3C8653CF13D0F140
Sequence:

MAGTVVLDDV ELREAQRDYL DFLDDEEDQG IYQNKVRELI SDNQYRLIVS VNDLRRKNEK 
RANRLLNNAF EELVAFQRAL KDFVASIDAT YAKQYEEFYI GLEGSFGSKH VSPRTLTSCF 
LSCVVCVEGI VTKCSLVRPK VVRSVHYCPA TKKTIERRYS DLTTLVAFPS SSVYPTKDEE 
NNPLETEYGL SVYKDHQTIT IQEMPEKAPA GQLPRSVDVI LDDDLVDKVK PGDRIQVVGT 
YRCLPGKKGC YTSGTFRTVL IACNVKQMSK DIQPAFSADD IAKIKKFSKT RSKDVFEQLA 
RSLAPSIHGH DYVKKAILCL LLGGVERELE NGSHIRGDIN ILLIGDPSVA KSQLLRYVLC 
TAPRAIPTTG RGSSGVGLTA AVTTDQETGE RRLEAGAMVL ADRGVVCIDE FDKMSDMDRT 
AIHEVMEQGR VTIAKAGIHA RLNARCSVLA AANPVYGRYD QYKTPMENIG LQDSLLSRFD 
LLFIMLDQMD PEQDREISDH VLRMHQYRAP GEQDGDALPL GSSVDILATD DPDFTQDDQQ 
DTRIYEKHDS LLHGTKKKKE KMVSAAFMKK YIHVAKIIKP TLTQESAAYI AEEYSRLRSQ 
DSMSSDTART SPVTARTLET LIRLATAHAK ARMSKTVDLQ DAEEAVELVQ YAYFKKVLEK 
EKKRKKASED ESDLEDEEEK SQEDTEQKRK RRKTHAKDGE SYDPYDFSEA ETQMPQVHTP 
KTDDSQEKTD DSQETQDSQK VELSEPRLKA FKAALLEVFQ EAHEQSVGML HLTESINRNR 
EEPFSSEEIQ ACLSRMQDDN QVMVSEGIVF LI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mcm3

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein. PubMed ID: 1549468

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. PubMed ID: 7925275

A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication. PubMed ID: 10733502

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337