Genular: Defining Cellular Identity and Function

Details for: Mcm7

Gene ID: 17220

Symbol: Mcm7

Ensembl ID: ENSMUSG00000029730

Description: minichromosome maintenance complex component 7

Associated with

Activation of atr in response to replication stress
(R-MMU-176187)
Activation of the pre-replicative complex
(R-MMU-68962)
Assembly of the pre-replicative complex
(R-MMU-68867)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Dna replication pre-initiation
(R-MMU-69002)
G1/s transition
(R-MMU-69206)
G2/m checkpoints
(R-MMU-69481)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Orc1 removal from chromatin
(R-MMU-68949)
S phase
(R-MMU-69242)
Switching of origins to a post-replicative state
(R-MMU-69052)
Synthesis of dna
(R-MMU-69239)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cell cycle
(GO:0007049)
Cell population proliferation
(GO:0008283)
Cellular response to xenobiotic stimulus
(GO:0071466)
Chromosome
(GO:0005694)
Cmg complex
(GO:0071162)
Cytosol
(GO:0005829)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna duplex unwinding
(GO:0032508)
Dna helicase activity
(GO:0003678)
Dna replication
(GO:0006260)
Dna replication initiation
(GO:0006270)
Dna strand elongation involved in dna replication
(GO:0006271)
Dna unwinding involved in dna replication
(GO:0006268)
Double-strand break repair via break-induced replication
(GO:0000727)
Helicase activity
(GO:0004386)
Hydrolase activity
(GO:0016787)
Mcm complex
(GO:0042555)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Premeiotic dna replication
(GO:0006279)
Protein binding
(GO:0005515)
Regulation of phosphorylation
(GO:0042325)
Single-stranded dna binding
(GO:0003697)
Single-stranded dna helicase activity
(GO:0017116)

Other Information

Proteins

DNA replication licensing factor MCM7

Genular Protein ID: 2202977799

Symbol: MCM7_MOUSE

Name: DNA replication licensing factor MCM7

UniProtKB Accession Codes:

Q61881

Database IDs:

Citations:

PubMed ID: 8566808

Title: Sequence of mouse CDC47, a member of the minichromosome maintenance (Mcm) family involved in the DNA replication licensing system.

PubMed ID: 8566808

DOI: 10.1016/0378-1119(95)00713-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10567526

Title: Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity.

PubMed ID: 10567526

DOI: 10.1128/mcb.19.12.8003

PubMed ID: 12207017

Title: Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex.

PubMed ID: 12207017

DOI: 10.1074/jbc.m205769200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 33590678

Title: CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle.

PubMed ID: 33590678

DOI: 10.15252/embr.202052164

Sequence Information:

Length: 719
Mass: 81211
Checksum: 019AE8E04BB8EB3C
Sequence:

MALKDYAIEK EKVKKFLQEF YYENELGKKQ FKYGTQLVHL AHREQVALYV DLDDIAEDDP 
ELVDSICENA KRYSRLFGDV VQELLPEYKE KEVVNKDVLD VYIEHRLMME QRSRDPGAVR 
NPQNQYPSEL MRRFELYFRG PSSSKPRVIR EVRADSVGKL LTVRGIVTRV SEVKPRMVVA 
TYTCDQCGAE TYQPIQSPTF MPLIMCPSQE CQTNRSGGRL YLQTRGSKFV KFQEMKIQEH 
SDQVPVGNIP RSITVVLEGE NTRIAQPGDH VSVTGIFLPV LRTGFQQMAQ GLLSETYLEA 
HWIVKMTKSD DDVSGAGELS SEELKQIAEE DFYEKLAASI APEIYGHEDV KKALLLLLVG 
GVDQSPQGMK IRGNIHICLM GDPGVAKSQL LSYIDRLAPR SQYTTGRGSS GVGLTAAVLR 
DSVSGELTLE GGALVLADQG VCCIDEFDKM AEADRTAIHE VMEQQTISIA KAGILTTLNA 
RCSILAAANP AYGRYNPRRS LEQNVQLPAA LLSRFDLLWL IQDRPDRDND LRLAQHITYV 
HQHSRQPPAQ FEPLDMKLMR RYIAMCHERQ PTVPESLADY ITAAYVEMRR EARASKDATY 
TSARTLLAIL RLSTALARLR MVDIVEKEDV NEAIRLMEMS KDSLLGEKGQ TARTQRPADV 
IFATIRELVS RGRSVHFSEA EQRCISRGFT PAQFQAALDE YEELNVWQVN TSRTRITFV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mcm7

Associated with

Other Information

Sequence of mouse CDC47, a member of the minichromosome maintenance (Mcm) family involved in the DNA replication licensing system. PubMed ID: 8566808

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity. PubMed ID: 10567526

Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex. PubMed ID: 12207017

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079