Details for: Mgrn1

Gene ID: 17237

Symbol: Mgrn1

Ensembl ID: ENSMUSG00000022517

Description: mahogunin, ring finger 1

Associated with

Other Information

Genular Protein ID: 3149064478

Symbol: MGRN1_MOUSE

Name: E3 ubiquitin-protein ligase MGRN1

UniProtKB Accession Codes:

Q9D074 Q3U5V9 Q3UDA1 Q6ZQ97 Q8BZM9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 4 CDD 1 ChiTaRS 1 DNASU 1 EC 2 EMBL 7 EPD 1 Ensembl 4 GO 16 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 3 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SAM 1 SMART 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 2 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14621295

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 14621295

DOI: 10.1093/dnares/10.4.167

PubMed ID: 12438443

Title: The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein.

PubMed ID: 12438443

DOI: 10.1172/jci16131

PubMed ID: 12560552

Title: Spongiform degeneration in mahoganoid mutant mice.

PubMed ID: 12560552

DOI: 10.1126/science.1079694

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17075880

Title: Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.

PubMed ID: 17075880

DOI: 10.1002/dvdy.20992

PubMed ID: 17083490

Title: Characterization of Mahogunin Ring Finger-1 expression in mice.

PubMed ID: 17083490

DOI: 10.1111/j.1600-0749.2006.00340.x

PubMed ID: 17720281

Title: Mitochondrial dysfunction precedes neurodegeneration in mahogunin (Mgrn1) mutant mice.

PubMed ID: 17720281

DOI: 10.1016/j.neurobiolaging.2007.07.012

PubMed ID: 19703557

Title: Abnormal regulation of TSG101 in mice with spongiform neurodegeneration.

PubMed ID: 19703557

DOI: 10.1016/j.bbadis.2009.08.009

PubMed ID: 19524515

Title: Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration.

PubMed ID: 19524515

DOI: 10.1016/j.cell.2009.03.042

PubMed ID: 19422019

Title: Transgenic analysis of the physiological functions of Mahogunin Ring Finger-1 isoforms.

PubMed ID: 19422019

DOI: 10.1002/dvg.20529

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 29290584

Title: CRISPR screens uncover genes that regulate target cell sensitivity to the morphogen sonic hedgehog.

PubMed ID: 29290584

DOI: 10.1016/j.devcel.2017.12.003

Sequence Information:

  • Length: 532
  • Mass: 58477
  • Checksum: 89C2C1A28F9417EE
  • Sequence:
    • MGSILSRRIA GVEDIDIQAN SAYRYPPKSG NYFASHFFMG GEKFDTPHPE GYLFGENMDL 
NFLGSRPVQF PYVTPAPHEP VKTLRSLVNI RKDSLRLVRY KEDADSPTED GEKPRVLYSL 
EFTFDADARV AITIYCQAVE ELVNGVAVYS CKNPSLQSET VHYKRGVSQQ FSLPSFKIDF 
SEWKDDELNF DLDRGVFPVV IQAVVDEGDV VEVTGHAHVL LAAFEKHVDG SFSVKPLKQK 
QIVDRVSYLL QEIYGIENKN NQETKPSDDE NSDNSSECVV CLSDLRDTLI LPCRHLCLCT 
SCADTLRYQA NNCPICRLPF RALLQIRAVR KKPGALSPIS FSPVLAQSVD HDEHSSSDSI 
PPGYEPISLL EALNGLRAVS PAIPSAPLYE EITYSGISDG LSQASCPLAG LDRIMESGLQ 
KGKTQSKSPD STLRSPSFPI HEEDEEKLSE DSDAPLPPSG VELVLRESSS PESFGTEEGD 
EPSLKQGSRV PSIDDVLQDG SPQHHGCSQP VPPADIYLPA LGPESCSVGI EE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.