Genular: Defining Cellular Identity and Function

Details for: Mdm4

Gene ID: 17248

Symbol: Mdm4

Ensembl ID: ENSMUSG00000054387

Description: transformed mouse 3T3 cell double minute 4

Associated with

Cell cycle
(R-MMU-1640170)
Cell cycle checkpoints
(R-MMU-69620)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Deubiquitination
(R-MMU-5688426)
G1/s dna damage checkpoints
(R-MMU-69615)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism of proteins
(R-MMU-392499)
Oncogene induced senescence
(R-MMU-2559585)
Oxidative stress induced senescence
(R-MMU-2559580)
P53-dependent g1 dna damage response
(R-MMU-69563)
P53-dependent g1/s dna damage checkpoint
(R-MMU-69580)
Post-translational protein modification
(R-MMU-597592)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 activity through methylation
(R-MMU-6804760)
Regulation of tp53 activity through phosphorylation
(R-MMU-6804756)
Regulation of tp53 degradation
(R-MMU-6804757)
Regulation of tp53 expression and degradation
(R-MMU-6806003)
Rna polymerase ii transcription
(R-MMU-73857)
Stabilization of p53
(R-MMU-69541)
Transcriptional regulation by tp53
(R-MMU-3700989)
Ub-specific processing proteases
(R-MMU-5689880)
Atrial septum development
(GO:0003283)
Atrioventricular valve morphogenesis
(GO:0003181)
Endocardial cushion morphogenesis
(GO:0003203)
Enzyme binding
(GO:0019899)
Heart valve development
(GO:0003170)
Metal ion binding
(GO:0046872)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
(GO:1902254)
Negative regulation of protein catabolic process
(GO:0042177)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of cell population proliferation
(GO:0008284)
Protein-containing complex assembly
(GO:0065003)
Protein binding
(GO:0005515)
Protein ubiquitination
(GO:0016567)
Regulation of cell cycle
(GO:0051726)
Regulation of heart rate
(GO:0002027)
Transcription repressor complex
(GO:0017053)
Ubiquitin-protein transferase activity
(GO:0004842)
Ventricular septum development
(GO:0003281)

Other Information

Proteins

Protein Mdm4
Q3UTC9_MOUSE

Genular Protein ID: 2594885275

Symbol: MDM4_MOUSE

Name: Protein Mdm4

UniProtKB Accession Codes:

O35618 Q9CYG1

Database IDs:

Citations:

PubMed ID: 8895579

Title: MDMX: a novel p53-binding protein with some functional properties of MDM2.

PubMed ID: 8895579

DOI: 10.1002/j.1460-2075.1996.tb00919.x

PubMed ID: 10075736

Title: A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity.

PubMed ID: 10075736

DOI: 10.1074/jbc.274.12.8299

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

Sequence Information:

Length: 489
Mass: 54963
Checksum: 85A7602AA9AAFD52
Sequence:

MTSHSTSAQC SASDSACRIS SEQISQVRPK LQLLKILHAA GAQGEVFTMK EVMHYLGQYI 
MVKQLYDQQE QHMVYCGGDL LGDLLGCQSF SVKDPSPLYD MLRKNLVTSA SINTDAAQTL 
ALAQDHTMDF PSQDRLKHGA TEYSNPRKRT EEEDTHTLPT SRHKCRDSRA DEDLIEHLSQ 
DETSRLDLDF EEWDVAGLPW WFLGNLRNNC IPKSNGSTDL QTNQDIGTAI VSDTTDDLWF 
LNETVSEQLG VGIKVEAANS EQTSEVGKTS NKKTVEVGKD DDLEDSRSLS DDTDVELTSE 
DEWQCTECKK FNSPSKRYCF RCWALRKDWY SDCSKLTHSL STSNITAIPE KKDNEGIDVP 
DCRRTISAPV VRPKDGYLKE EKPRFDPCNS VGFLDLAHSS ESQEIISSAR EQTDIFSEQK 
AETESMEDFQ NVLKPCSLCE KRPRDGNIIH GKTSHLTTCF HCARRLKKSG ASCPACKKEI 
QLVIKVFIA

Genular Protein ID: 2291337039

Symbol: Q3UTC9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UTC9

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 490
Mass: 55091
Checksum: E3E1BA96A8C2BCFE
Sequence:

MTSHSTSAQC SASDSACRIS SEQISQQVRP KLQLLKILHA AGAQGEVFTM KEVMHYLGQY 
IMVKQLYDQQ EQHMVYCGGD LLGDLLGCQS FSVKDPSPLY DMLRKNLVTS ASINTDAAQT 
LALAQDHTMD FPSQDRLKHG ATEYSNPRKR TEEEDTHTLP TSRHKCRDSR ADEDLIEHLS 
QDETSRLDLD FEEWDVAGLP WWFLGNLRNN CIPKSNGSTD LQTNQDIGTA IVSDTTDDLW 
FLNETVSEQL GVGIKVEAAN SEQTSEVGKT SNKKTVEVGK DDDLEDSRSL SDDTDVELTS 
EDEWQCTECK KFNSPSKRYC FRCWALRKDW YSDCSKLTHS LSTSNITAIP EKKDNEGIDV 
PDCRRTISAP VVRPKDGYLK EEKPRFDPCN SVGFLDLAHS SESQEIISSA REQTDIFSEQ 
KAETESMEDF QNVLKPCSLC EKRPRDGNII HGKTSHLTTC FHCARRLKKS GASCPACKKE 
IQLVIKVFIA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mdm4

Associated with

Other Information

MDMX: a novel p53-binding protein with some functional properties of MDM2. PubMed ID: 8895579

A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity. PubMed ID: 10075736

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303