Genular: Defining Cellular Identity and Function

Details for: Mef2a

Gene ID: 17258

Symbol: Mef2a

Ensembl ID: ENSMUSG00000030557

Description: myocyte enhancer factor 2A

Associated with

Apoptotic process
(GO:0006915)
Cardiac conduction
(GO:0061337)
Cell differentiation
(GO:0030154)
Cellular response to calcium ion
(GO:0071277)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Cytosol
(GO:0005829)
Dendrite morphogenesis
(GO:0048813)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Dna-templated transcription
(GO:0006351)
Dna binding
(GO:0003677)
Erk5 cascade
(GO:0070375)
Heart development
(GO:0007507)
Histone acetyltransferase binding
(GO:0035035)
Histone deacetylase binding
(GO:0042826)
Mapk cascade
(GO:0000165)
Mitochondrial genome maintenance
(GO:0000002)
Mitochondrion distribution
(GO:0048311)
Multicellular organism development
(GO:0007275)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nervous system development
(GO:0007399)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of cardiac muscle hypertrophy
(GO:0010613)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein heterodimerization activity
(GO:0046982)
Protein kinase binding
(GO:0019901)
Regulation of dna-templated transcription
(GO:0006355)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sequence-specific dna binding
(GO:0043565)
Smad binding
(GO:0046332)
Transcription regulator complex
(GO:0005667)
Ventricular cardiac myofibril assembly
(GO:0055005)

Other Information

Proteins

Myocyte-specific enhancer factor 2A

Genular Protein ID: 2103265762

Symbol: MEF2A_MOUSE

Name: Myocyte-specific enhancer factor 2A

UniProtKB Accession Codes:

Q60929 Q3V155 Q4VA09 Q6P8Q3

Database IDs:

Citations:

PubMed ID: 9013788

Title: The expression of MEF2 genes is implicated in CNS neuronal differentiation.

PubMed ID: 9013788

DOI: 10.1016/s0169-328x(96)00135-0

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11585834

Title: Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7.

PubMed ID: 11585834

DOI: 10.1074/jbc.m107631200

PubMed ID: 15834131

Title: Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.

PubMed ID: 15834131

DOI: 10.1074/jbc.m502491200

PubMed ID: 17785444

Title: Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development.

PubMed ID: 17785444

DOI: 10.1128/mcb.01481-07

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 498
Mass: 53579
Checksum: FE291C3E3E0A5E70
Sequence:

MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST 
DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCESPD ADDYFEHSPL SEDRFSKLNE 
DSDFIFKRGP PGLPPQNFSM SVTVPVTSPN ALSYTNPGSS LVSPSLAASS TLADSSMLSP 
PPATLHRNVS PGAPQRPPST GSASGMLSTT DLTVPNGAGN SPVGNGFVNS RASPNLIGNT 
GANSLGKVMP TKSPPPPGGG SLGMNSRKPD LRVVIPPSSK GMMPPLSEEE ELELNAQRIS 
SSQATQPLAT PVVSVTTPSL PPQGLVYSAM PTAYNTDYSL TSADLSALQG FTSPGMLSLG 
QASAWQQHHL GQAALSSLVA GGQLSQGSNL SINTNQNINI KSEPISPPRD RMTPSGFQQQ 
QQQPQQQPPP QPPQPQPRQE MGRSPVDSLS SSSSSYDGSD REDPRGDFHS PIVLGRPPNT 
EDRESPSVKR MRMDTWVT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mef2a

Associated with

Other Information

The expression of MEF2 genes is implicated in CNS neuronal differentiation. PubMed ID: 9013788

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7. PubMed ID: 11585834

Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain. PubMed ID: 15834131

Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development. PubMed ID: 17785444

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337