Details for: Mef2c

Gene ID: 17260

Symbol: Mef2c

Ensembl ID: ENSMUSG00000005583

Description: myocyte enhancer factor 2C

Associated with

Other Information

Genular Protein ID: 1222208045

Symbol: MEF2C_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8CFN5 Q8R0H1 Q9D7L0 Q9QW20

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 5 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 ELM 1 EMBL 4 Ensembl 7 ExpressionAtlas 1 GO 100 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 2 MINT 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 Reactome 1 RefSeq 19 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 3 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8506376

Title: Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors.

PubMed ID: 8506376

DOI: 10.1073/pnas.90.11.5282

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9013788

Title: The expression of MEF2 genes is implicated in CNS neuronal differentiation.

PubMed ID: 9013788

DOI: 10.1016/s0169-328x(96)00135-0

PubMed ID: 8663403

Title: Phosphorylation of the MADS-Box transcription factor MEF2C enhances its DNA binding activity.

PubMed ID: 8663403

DOI: 10.1074/jbc.271.29.17199

PubMed ID: 9162005

Title: Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.

PubMed ID: 9162005

DOI: 10.1126/science.276.5317.1404

PubMed ID: 9778514

Title: Requirement of the MADS-box transcription factor MEF2C for vascular development.

PubMed ID: 9778514

DOI: 10.1242/dev.125.22.4565

PubMed ID: 11554755

Title: SOX18 directly interacts with MEF2C in endothelial cells.

PubMed ID: 11554755

DOI: 10.1006/bbrc.2001.5589

PubMed ID: 11279209

Title: A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

PubMed ID: 11279209

DOI: 10.1074/jbc.m101508200

PubMed ID: 11713257

Title: The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2.

PubMed ID: 11713257

DOI: 10.1074/jbc.m109835200

PubMed ID: 15340086

Title: Phosphorylation and alternative pre-mRNA splicing converge to regulate myocyte enhancer factor 2C activity.

PubMed ID: 15340086

DOI: 10.1128/mcb.24.18.8264-8275.2004

PubMed ID: 15834131

Title: Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.

PubMed ID: 15834131

DOI: 10.1074/jbc.m502491200

PubMed ID: 16818234

Title: Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR.

PubMed ID: 16818234

DOI: 10.1016/j.molcel.2006.05.026

PubMed ID: 18438409

Title: Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation.

PubMed ID: 18438409

DOI: 10.1038/ni.1609

PubMed ID: 18086704

Title: Differentiation-dependent lysine 4 acetylation enhances MEF2C binding to DNA in skeletal muscle cells.

PubMed ID: 18086704

DOI: 10.1093/nar/gkm1114

PubMed ID: 18599438

Title: MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function.

PubMed ID: 18599438

DOI: 10.1073/pnas.0802679105

PubMed ID: 18599437

Title: Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo.

PubMed ID: 18599437

DOI: 10.1073/pnas.0802876105

PubMed ID: 19211936

Title: Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis.

PubMed ID: 19211936

DOI: 10.1182/blood-2008-07-167577

PubMed ID: 19753306

Title: Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells.

PubMed ID: 19753306

DOI: 10.1371/journal.pone.0007031

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20139090

Title: The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice.

PubMed ID: 20139090

DOI: 10.1074/jbc.m110.106856

PubMed ID: 22956541

Title: Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2.

PubMed ID: 22956541

DOI: 10.1242/jcs.105239

PubMed ID: 30409805

Title: E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator.

PubMed ID: 30409805

DOI: 10.1126/science.aan3303

Sequence Information:

  • Length: 474
  • Mass: 51278
  • Checksum: CEFC2DB21E89632A
  • Sequence:
    • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST 
DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCDSPD PDADDSVGHS PESEDKYRKI 
NEDIDLMISR QRLCAVPPPS FEMPVTIPVS SHNSLVYSNP VSTLGNPNLL PLAHPSLQRN 
SMSPGVTHRP PSAGNTGGLM GGDLTSGAGT SAGNGYGNPR NSPGLLVSPG NLNKNIQAKS 
PPPMNLGMNN RKPDLRVLIP PGSKNTMPSV SEDVDLLLNQ RINNSQSAQS LATPVVSVAT 
PTLPGQGMGG YPSAISTTYG TEYSLSSADL SSLSGFNTAS ALHLGSVTGW QQQHLHNMPP 
SALSQLGACT STHLSQSSNL SLPSTQSLSI KSEPVSPPRD RTTTPSRYPQ HTTRHEAGRS 
PVDSLSSCSS SYDGSDREDH RNEFHSPIGL TRPSPDERES PSVKRMRLSE GWAT

Genular Protein ID: 1430499653

Symbol: Q3V1B5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3V1B5

Database IDs:

AGR 1 ARBA 8 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 5 Gene3D 1 InterPro 4 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 2 PhylomeDB 1 RefSeq 5 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 466
  • Mass: 50393
  • Checksum: F06A89C9ACD779AE
  • Sequence:
    • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST 
DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCDSPD PDADDSVGHS PESEDKYRKI 
NEDIDLMISR QRLCAVPPPS FEMPVTIPVS SHNSLVYSNP VSTLGNPNLL PLAHPSLQRN 
SMSPGVTHRP PSAGNTGGLM GGDLTSGAGT SAGNGYGNPR NSPGLLVSPG NLNKNIQAKS 
PPPMNLGMNN RKPDLRVLIP PGSKNTMPSV NQRINNSQSA QSLATPVVSV ATPTLPGQGM 
GGYPSAISTT YGTEYSLSSA DLSSLSGFNT ASALHLGSVT GWQQQHLHNM PPSALSQLGA 
CTSTHLSQSS NLSLPSTQSL SIKSEPVSPP RDRTTTPSRY PQHTTRHEAG RSPVDSLSSC 
SSSYDGSDRE DHRNEFHSPI GLTRPSPDER ESPSVKRMRL SEGWAT

Genular Protein ID: 580473501

Symbol: A0A0G2JEC2_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0G2JEC2

Database IDs:

AGR 1 ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 InterPro 4 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 434
  • Mass: 47071
  • Checksum: C4787ACE5A321E8F
  • Sequence:
    • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST 
DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCDSPD PDADDSVGHS PESEDKYRKI 
NEDIDLMISR QRLCAVPPPS FEMPVTIPVS SHNSLVYSNP VSTLGNPNLL PLAHPSLQRN 
SMSPGVTHRP PSAGNTGGLM GGDLTSGAGT SAGNGYGNPR NSPGLLVSPG NLNKNIQAKS 
PPPMNLGMNN RKPDLRVLIP PGSKNTMPSV NQRINNSQSA QSLATPVVSV ATPTLPGQGM 
GGYPSAISTT YGTEYSLSSA DLSSLSGFNT ASALHLGSVT GWQQQHLHNM PPSALSQLGD 
RTTTPSRYPQ HTTRHEAGRS PVDSLSSCSS SYDGSDREDH RNEFHSPIGL TRPSPDERES 
PSVKRMRLSE GWAT

Genular Protein ID: 3582009980

Symbol: A0A0H2UH28_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0H2UH28

Database IDs:

AGR 1 ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 25 Gene3D 1 GeneTree 1 InterPro 4 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 484
  • Mass: 52369
  • Checksum: 3C6DABE43AD54BE8
  • Sequence:
    • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST 
DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCDSPD PDADDSALNK KENKGSESPD 
PDSSYALTPR TEEKYKKINE EFDNMIKSHK IPAVPPPSFE MPVTIPVSSH NSLVYSNPVS 
TLGNPNLLPL AHPSLQRNSM SPGVTHRPPS AGNTGGLMGG DLTSGAGTSA GNGYGNPRNS 
PGLLVSPGNL NKNIQAKSPP PMNLGMNNRK PDLRVLIPPG SKNTMPSVNQ RINNSQSAQS 
LATPVVSVAT PTLPGQGMGG YPSAISTTYG TEYSLSSADL SSLSGFNTAS ALHLGSVTGW 
QQQHLHNMPP SALSQLGACT STHLSQSSNL SLPSTQSLSI KSEPVSPPRD RTTTPSRYPQ 
HTTRHEAGRS PVDSLSSCSS SYDGSDREDH RNEFHSPIGL TRPSPDERES PSVKRMRLSE 
GWAT

Genular Protein ID: 1412303620

Symbol: A0A0H2UKB6_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0H2UKB6

Database IDs:

AGR 1 ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 InterPro 4 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 464
  • Mass: 50283
  • Checksum: D87EC5BA15FCA378
  • Sequence:
    • MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST 
DMDKVLLKYT EYNEPHESRT NSDIVEALNK KENKGSESPD PDSSYALTPR TEEKYKKINE 
EFDNMIKSHK IPAVPPPSFE MPVTIPVSSH NSLVYSNPVS TLGNPNLLPL AHPSLQRNSM 
SPGVTHRPPS AGNTGGLMGG DLTSGAGTSA GNGYGNPRNS PGLLVSPGNL NKNIQAKSPP 
PMNLGMNNRK PDLRVLIPPG SKNTMPSVNQ RINNSQSAQS LATPVVSVAT PTLPGQGMGG 
YPSAISTTYG TEYSLSSADL SSLSGFNTAS ALHLGSVTGW QQQHLHNMPP SALSQLGACT 
STHLSQSSNL SLPSTQSLSI KSEPVSPPRD RTTTPSRYPQ HTTRHEAGRS PVDSLSSCSS 
SYDGSDREDH RNEFHSPIGL TRPSPDERES PSVKRMRLSE GWAT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.