Genular: Defining Cellular Identity and Function

Details for: Meox1

Gene ID: 17285

Symbol: Meox1

Ensembl ID: ENSMUSG00000001493

Description: mesenchyme homeobox 1

Associated with

Chromatin binding
(GO:0003682)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Hmg box domain binding
(GO:0071837)
Multicellular organism development
(GO:0007275)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sclerotome development
(GO:0061056)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Somite development
(GO:0061053)
Somite specification
(GO:0001757)

Other Information

Proteins

Homeobox protein MOX-1

Genular Protein ID: 1107181142

Symbol: MEOX1_MOUSE

Name: Homeobox protein MOX-1

UniProtKB Accession Codes:

P32442 Q543E8

Database IDs:

Citations:

PubMed ID: 1363541

Title: Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos.

PubMed ID: 1363541

DOI: 10.1242/dev.116.4.1123

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12925591

Title: The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites.

PubMed ID: 12925591

DOI: 10.1242/dev.00687

PubMed ID: 15039437

Title: Disruption of Meox or Gli activity ablates skeletal myogenesis in P19 cells.

PubMed ID: 15039437

DOI: 10.1074/jbc.m312612200

PubMed ID: 15024065

Title: Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter.

PubMed ID: 15024065

DOI: 10.1128/mcb.24.7.2757-2766.2004

PubMed ID: 18417617

Title: Developmental origin of smooth muscle cells in the descending aorta in mice.

PubMed ID: 18417617

DOI: 10.1242/dev.020958

PubMed ID: 19520072

Title: Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.

PubMed ID: 19520072

DOI: 10.1016/j.ydbio.2009.06.006

PubMed ID: 22206000

Title: Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells.

PubMed ID: 22206000

DOI: 10.1371/journal.pone.0029099

Sequence Information:

Length: 253
Mass: 27980
Checksum: 5B8757EFE503EDDF
Sequence:

MDPVANSCVR NPQPPAPVWG CLRNPHSEDS SASGLSHYPP TPFSFHQKSD FPATAAYPDF 
SASCLAATPH SLPRTERIFN EQHPAFPQTP DWHFPISEAG QRLNLGPAGS AREMGAGSPG 
LVDGTAGLGE DCMVLGTIAN ETEKKSSRRK KERSDNQENG GGKPEGSSKA RKERTAFTKE 
QLRELEAEFA HHNYLTRLRR YEIAVNLDLS ERQVKVWFQN RRMKWKRVKG GQPVSPQEQD 
REDGDSAASP SSE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Meox1

Associated with

Other Information

Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. PubMed ID: 1363541

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. PubMed ID: 12925591

Disruption of Meox or Gli activity ablates skeletal myogenesis in P19 cells. PubMed ID: 15039437

Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter. PubMed ID: 15024065

Developmental origin of smooth muscle cells in the descending aorta in mice. PubMed ID: 18417617

Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. PubMed ID: 19520072

Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. PubMed ID: 22206000