Genular: Defining Cellular Identity and Function

Details for: Meox2

Gene ID: 17286

Symbol: Meox2

Ensembl ID: ENSMUSG00000036144

Description: mesenchyme homeobox 2

Associated with

Angiogenesis
(GO:0001525)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Fibroblast proliferation
(GO:0048144)
Limb development
(GO:0060173)
Multicellular organism development
(GO:0007275)
Negative regulation of cell migration involved in sprouting angiogenesis
(GO:0090051)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Roof of mouth development
(GO:0060021)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Skeletal muscle tissue development
(GO:0007519)
Somite development
(GO:0061053)
Somite specification
(GO:0001757)

Other Information

Proteins

MEOX2_MOUSE

Genular Protein ID: 3747745303

Symbol: MEOX2_MOUSE

Name: N/A

UniProtKB Accession Codes:

P32443 Q544T6

Database IDs:

Citations:

PubMed ID: 1363541

Title: Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos.

PubMed ID: 1363541

DOI: 10.1242/dev.116.4.1123

PubMed ID: 7909944

Title: Amino acid sequence of Mox-2 and comparison to its Xenopus and rat homologs.

PubMed ID: 7909944

DOI: 10.1093/nar/21.21.4982

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 7623821

Title: Regulation of Gax homeobox gene transcription by a combination of positive factors including myocyte-specific enhancer factor 2.

PubMed ID: 7623821

DOI: 10.1128/mcb.15.8.4272

PubMed ID: 10403250

Title: Mox2 is a component of the genetic hierarchy controlling limb muscle development.

PubMed ID: 10403250

DOI: 10.1038/21892

PubMed ID: 12925591

Title: The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites.

PubMed ID: 12925591

DOI: 10.1242/dev.00687

PubMed ID: 16116430

Title: Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease.

PubMed ID: 16116430

DOI: 10.1038/nm1287

PubMed ID: 16284941

Title: Analysis of Meox-2 mutant mice reveals a novel postfusion-based cleft palate.

PubMed ID: 16284941

DOI: 10.1002/dvdy.20641

PubMed ID: 25561514

Title: Meox2/Tcf15 heterodimers program the heart capillary endothelium for cardiac fatty acid uptake.

PubMed ID: 25561514

DOI: 10.1161/circulationaha.114.013721

Sequence Information:

Length: 303
Mass: 33506
Checksum: 41BD05FC39AA4427
Sequence:

MEHPLFGCLR SPHATAQGLH PFSQSSLALH GRSDHMSYPE LSTSSSSCII AGYPNEEGMF 
ASQHHRGHHH HHHHHHHHHQ QQQHQALQSN WHLPQMSSPP SAARHSLCLQ PDSGGPPELG 
SSPPVLCSNS SSLGSSTPTG AACAPGDYGR QALSPADVEK RSGSKRKSDS SDSQEGNYKS 
EVNSKPRKER TAFTKEQIRE LEAEFAHHNY LTRLRRYEIA VNLDLTERQV KVWFQNRRMK 
WKRVKGGQQG AAAREKELVN VKKGTLLPSE LSGIGAATLQ QTGDSLANED SRDSDHSSEH 
AHL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Meox2

Associated with

Other Information

Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. PubMed ID: 1363541

Amino acid sequence of Mox-2 and comparison to its Xenopus and rat homologs. PubMed ID: 7909944

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Regulation of Gax homeobox gene transcription by a combination of positive factors including myocyte-specific enhancer factor 2. PubMed ID: 7623821

Mox2 is a component of the genetic hierarchy controlling limb muscle development. PubMed ID: 10403250

The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. PubMed ID: 12925591

Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. PubMed ID: 16116430

Analysis of Meox-2 mutant mice reveals a novel postfusion-based cleft palate. PubMed ID: 16284941

Meox2/Tcf15 heterodimers program the heart capillary endothelium for cardiac fatty acid uptake. PubMed ID: 25561514