Details for: Mertk
Associated with
Other Information
Genular Protein ID: 3285365530
Symbol: MERTK_MOUSE
Name: Tyrosine-protein kinase Mer
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7784083
Title: Cloning and developmental expression analysis of the murine c-mer tyrosine kinase.
PubMed ID: 7784083
PubMed ID: 10227296
Title: Tyro-3 family receptors are essential regulators of mammalian spermatogenesis.
PubMed ID: 10227296
DOI: 10.1038/19554
PubMed ID: 9891051
Title: Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB.
PubMed ID: 9891051
PubMed ID: 12884290
Title: The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity.
PubMed ID: 12884290
PubMed ID: 14704368
Title: The receptor tyrosine kinase MerTK activates phospholipase C gamma2 during recognition of apoptotic thymocytes by murine macrophages.
PubMed ID: 14704368
DOI: 10.1189/jlb.0903439
PubMed ID: 15673687
Title: A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells.
PubMed ID: 15673687
DOI: 10.1242/jcs.01632
PubMed ID: 18039660
Title: Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation.
PubMed ID: 18039660
PubMed ID: 19117932
Title: Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis.
PubMed ID: 19117932
DOI: 10.1167/iovs.08-3058
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20978472
Title: Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis.
PubMed ID: 20978472
PubMed ID: 20363878
Title: Sertoli cell-initiated testicular innate immune response through toll-like receptor-3 activation is negatively regulated by Tyro3, Axl, and mer receptors.
PubMed ID: 20363878
DOI: 10.1210/en.2009-1498
PubMed ID: 21792939
Sequence Information:
- Length: 994
- Mass: 110157
- Checksum: 603C09FA11F76FE0
- Sequence:
MVLAPLLLGL LLLPALWSGG TAEKWEETEL DQLFSGPLPG RLPVNHRPFS APHSSRDQLP PPQTGRSHPA HTAAPQVTST ASKLLPPVAF NHTIGHIVLS EHKNVKFNCS INIPNTYQET AGISWWKDGK ELLGAHHSIT QFYPDEEGVS IIALFSIASV QRSDNGSYFC KMKVNNREIV SDPIYVEVQG LPYFIKQPES VNVTRNTAFN LTCQAVGPPE PVNIFWVQNS SRVNEKPERS PSVLTVPGLT ETAVFSCEAH NDKGLTVSKG VHINIKVIPS PPTEVHILNS TAHSILVSWV PGFDGYSPLQ NCSIQVKEAD RLSNGSVMVF NTSASPHLYE IQQLQALANY SIAVSCRNEI GWSAVSPWIL ASTTEGAPSV APLNITVFLN ESNNILDIRW TKPPIKRQDG ELVGYRISHV WESAGTYKEL SEEVSQNGSW AQIPVQIHNA TCTVRIAAIT KGGIGPFSEP VNIIIPEHSK VDYAPSSTPA PGNTDSMFII LGCFCGFILI GLILCISLAL RRRVQETKFG GAFSEEDSQL VVNYRAKKSF CRRAIELTLQ SLGVSEELQN KLEDVVIDRN LLVLGKVLGE GEFGSVMEGN LKQEDGTSQK VAVKTMKLDN FSQREIEEFL SEAACMKDFN HPNVIRLLGV CIELSSQGIP KPMVILPFMK YGDLHTFLLY SRLNTGPKYI HLQTLLKFMM DIAQGMEYLS NRNFLHRDLA ARNCMLRDDM TVCVADFGLS KKIYSGDYYR QGRIAKMPVK WIAIESLADR VYTSKSDVWA FGVTMWEITT RGMTPYPGVQ NHEMYDYLLH GHRLKQPEDC LDELYDIMYS CWSADPLDRP TFSVLRLQLE KLSESLPDAQ DKESIIYINT QLLESCEGIA NGPSLTGLDM NIDPDSIIAS CTPGAAVSVV TAEVHENNLR EERYILNGGN EEWEDVSSTP FAAVTPEKDG VLPEDRLTKN GVSWSHHSTL PLGSPSPDEL LFVDDSLEDS EVLM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.