Details for: Mettl1

Gene ID: 17299

Symbol: Mettl1

Ensembl ID: ENSMUSG00000006732

Description: methyltransferase 1, tRNA methylguanosine

Associated with

Other Information

Genular Protein ID: 451157832

Symbol: TRMB_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9Z120 Q3TU83 Q921G5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 20 DNASU 1 EC 1 EMBL 5 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 14 Gene3D 1 GeneTree 1 Genevisible 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 Rhea 11 SAM 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10329009

Title: Molecular analysis of METTL1, a novel human methyltransferase-like gene with a high degree of phylogenetic conservation.

PubMed ID: 10329009

DOI: 10.1006/geno.1999.5780

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 29983320

Title: Mettl1/Wdr4-mediated m7G tRNA methylome is required for normal mRNA translation and embryonic stem cell self-renewal and differentiation.

PubMed ID: 29983320

DOI: 10.1016/j.molcel.2018.06.001

PubMed ID: 34352206

Title: N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression.

PubMed ID: 34352206

DOI: 10.1016/j.molcel.2021.07.003

Sequence Information:

  • Length: 268
  • Mass: 30603
  • Checksum: 1DAE1EEAA4A07627
  • Sequence:
    • MMAGAEAPQP QKRYYRQRAH SNPMADHTLR YPVKPEEMDW SELYPEFFAP LIQNKSHDDP 
KDEKEKHSGA QVEFADIGCG YGGLLVALSP LFPDTLILGL EIRVKVSDYV QDRIRALRAA 
PGGGFQNIAC LRSNAMKHLP NFFRKGQLAK MFFLFPDPHF KRTKHKWRII SPTLLAEYAY 
VLRVGGLVYT VTDVPELHEW MCTHFEEHPL FERVPLEELS EDPIVEHLGS STEEGKKVLR 
NGGKNFPAVF RRIQDPLLQA VTPNPTLP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.