Details for: AFM

Gene ID: 173

Symbol: AFM

Ensembl ID: ENSG00000079557

Description: afamin

Associated with

Other Information

Genular Protein ID: 1924026511

Symbol: AFAM_HUMAN

Name: Afamin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7517938

Title: Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family.

PubMed ID: 7517938

DOI: 10.1016/s0021-9258(17)32429-8

PubMed ID: 8755513

Title: Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene family.

PubMed ID: 8755513

DOI: 10.1073/pnas.93.15.7557

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7875606

Title: Identification of rat alpha-albumin and cDNA cloning of its human ortholog.

PubMed ID: 7875606

DOI: 10.1016/0378-1119(94)00745-e

PubMed ID: 15952736

Title: Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.

PubMed ID: 15952736

DOI: 10.1021/pr0500105

PubMed ID: 12463752

Title: Characterization of the vitamin E-binding properties of human plasma afamin.

PubMed ID: 12463752

DOI: 10.1021/bi026513v

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 19046407

Title: Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier.

PubMed ID: 19046407

DOI: 10.1111/j.1471-4159.2008.05796.x

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 26902720

Title: Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/alpha-albumin.

PubMed ID: 26902720

DOI: 10.7554/elife.11621

PubMed ID: 29153507

Title: Structural Evidence for a Role of the Multi-functional Human Glycoprotein Afamin in Wnt Transport.

PubMed ID: 29153507

DOI: 10.1016/j.str.2017.10.006

Sequence Information:

  • Length: 599
  • Mass: 69069
  • Checksum: D594E75E20D308AB
  • Sequence:
  • MKLLKLTGFI FFLFFLTESL TLPTQPRDIE NFNSTQKFIE DNIEYITIIA FAQYVQEATF 
    EEMEKLVKDM VEYKDRCMAD KTLPECSKLP NNVLQEKICA MEGLPQKHNF SHCCSKVDAQ 
    RRLCFFYNKK SDVGFLPPFP TLDPEEKCQA YESNRESLLN HFLYEVARRN PFVFAPTLLT 
    VAVHFEEVAK SCCEEQNKVN CLQTRAIPVT QYLKAFSSYQ KHVCGALLKF GTKVVHFIYI 
    AILSQKFPKI EFKELISLVE DVSSNYDGCC EGDVVQCIRD TSKVMNHICS KQDSISSKIK 
    ECCEKKIPER GQCIINSNKD DRPKDLSLRE GKFTDSENVC QERDADPDTF FAKFTFEYSR 
    RHPDLSIPEL LRIVQIYKDL LRNCCNTENP PGCYRYAEDK FNETTEKSLK MVQQECKHFQ 
    NLGKDGLKYH YLIRLTKIAP QLSTEELVSL GEKMVTAFTT CCTLSEEFAC VDNLADLVFG 
    ELCGVNENRT INPAVDHCCK TNFAFRRPCF ESLKADKTYV PPPFSQDLFT FHADMCQSQN 
    EELQRKTDRF LVNLVKLKHE LTDEELQSLF TNFANVVDKC CKAESPEVCF NEESPKIGN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.