Details for: Mfng

Gene ID: 17305

Symbol: Mfng

Ensembl ID: ENSMUSG00000018169

Description: MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Associated with

Other Information

Genular Protein ID: 2124054888

Symbol: MFNG_MOUSE

Name: O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

UniProtKB Accession Codes:

O09008

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID-ORCS 1 CAZy 1 CCDS 1 CTD 1 ChEBI 13 DNASU 1 EC 2 EMBL 3 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 2 PIRSF 1 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 Rhea 6 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9187150

Title: A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

PubMed ID: 9187150

DOI: 10.1242/dev.124.11.2245

PubMed ID: 9207795

Title: Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila.

PubMed ID: 9207795

DOI: 10.1038/ng0797-283

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10935626

Title: Fringe is a glycosyltransferase that modifies Notch.

PubMed ID: 10935626

DOI: 10.1038/35019000

PubMed ID: 16221665

Title: Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats.

PubMed ID: 16221665

DOI: 10.1074/jbc.m509552200

PubMed ID: 28089369

Title: Deciphering the fringe-mediated notch code: identification of activating and inhibiting sites allowing discrimination between ligands.

PubMed ID: 28089369

DOI: 10.1016/j.devcel.2016.12.013

PubMed ID: 16964258

Title: Structural insights into the Notch-modifying glycosyltransferase Fringe.

PubMed ID: 16964258

DOI: 10.1038/nsmb1144

Sequence Information:

  • Length: 321
  • Mass: 36200
  • Checksum: 76EBCEC2314C50CD
  • Sequence:
    • MHCRLFRGMA GALFTLLCVG LLSLRYHSSL SQRMIQGALR LNQRNPGPLE LQLGDIFIAV 
KTTWAFHRSR LDLLLDTWVS RIRQQTFIFT DSPDERLQER LGPHLVVTNC SAEHSHPALS 
CKMAAEFDAF LVSGLRWFCH VDDDNYVNPK ALLQLLKTFP QDRDVYVGKP SLNRPIHASE 
LQSKNRTKLV RFWFATGGAG FCINRQLALK MVPWASGSHF VDTSALIRLP DDCTVGYIIE 
CKLGGRLQPS PLFHSHLETL QLLGAAQLPE QVTLSYGVFE GKLNVIKLPG PFSHEEDPSR 
FRSLHCLLYP DTPWCPLLAA P

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.