Genular: Defining Cellular Identity and Function

Details for: Mmp11

Gene ID: 17385

Symbol: Mmp11

Ensembl ID: ENSMUSG00000000901

Description: matrix metallopeptidase 11

Associated with

Activation of matrix metalloproteinases
(R-MMU-1592389)
Collagen degradation
(R-MMU-1442490)
Degradation of the extracellular matrix
(R-MMU-1474228)
Basement membrane organization
(GO:0071711)
Collagen catabolic process
(GO:0030574)
Collagen fibril organization
(GO:0030199)
Extracellular matrix
(GO:0031012)
Extracellular matrix organization
(GO:0030198)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hydrolase activity
(GO:0016787)
Metal ion binding
(GO:0046872)
Metalloendopeptidase activity
(GO:0004222)
Metallopeptidase activity
(GO:0008237)
Negative regulation of fat cell differentiation
(GO:0045599)
Peptidase activity
(GO:0008233)
Proteolysis
(GO:0006508)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Stromelysin-3

Genular Protein ID: 3716503106

Symbol: MMP11_MOUSE

Name: Stromelysin-3

UniProtKB Accession Codes:

Q02853

Database IDs:

Citations:

PubMed ID: 1429845

Title: The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis.

PubMed ID: 1429845

DOI: 10.1083/jcb.119.4.997

PubMed ID: 11254383

Title: Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state.

PubMed ID: 11254383

DOI: 10.1006/jmbi.2001.4493

Sequence Information:

Length: 492
Mass: 55441
Checksum: B54E260E4AB3D7C3
Sequence:

MARAACLLRA ISRVLLLPLP LLLLLLLLLP SPLMARARPP ESHRHHPVKK GPRLLHAALP 
NTLTSVPASH WVPSPAGSSR PLRCGVPDLP DVLNARNRQK RFVLSGGRWE KTDLTYRILR 
FPWQLVREQV RQTVAEALQV WSEVTPLTFT EVHEGRADIM IDFARYWHGD NLPFDGPGGI 
LAHAFFPKTH REGDVHFDYD ETWTIGDNQG TDLLQVAAHE FGHVLGLQHT TAAKALMSPF 
YTFRYPLSLS PDDRRGIQHL YGRPQMAPTS PAPTLSSQAG TDTNEIALLE PETPPDVCET 
SFDAVSTIRG ELFFFKAGFV WRLRSGRLQP GYPALASRHW QGLPSPVDAA FEDAQGQIWF 
FQGAQYWVYD GEKPVLGPAP LSKLGLQGSP VHAALVWGPE KNKIYFFRGG DYWRFHPRTQ 
RVDNPVPRRS TDWRGVPSEI DAAFQDAEGY AYFLRGHLYW KFDPVKVKVL EGFPRPVGPD 
FFDCAEPANT FR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.