Genular: Defining Cellular Identity and Function

Details for: Mmp24

Gene ID: 17391

Symbol: Mmp24

Ensembl ID: ENSMUSG00000027612

Description: matrix metallopeptidase 24

Associated with

Activation of matrix metalloproteinases
(R-MMU-1592389)
Degradation of the extracellular matrix
(R-MMU-1474228)
Cadherin binding
(GO:0045296)
Cell-cell adhesion mediated by cadherin
(GO:0044331)
Cell-cell adhesion via plasma-membrane adhesion molecules
(GO:0098742)
Cell adhesion
(GO:0007155)
Collagen catabolic process
(GO:0030574)
Detection of temperature stimulus involved in sensory perception of pain
(GO:0050965)
Extracellular matrix
(GO:0031012)
Extracellular matrix organization
(GO:0030198)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Glial cell differentiation
(GO:0010001)
Golgi apparatus
(GO:0005794)
Hydrolase activity
(GO:0016787)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Metalloendopeptidase activity
(GO:0004222)
Metallopeptidase activity
(GO:0008237)
Neuronal stem cell population maintenance
(GO:0097150)
Peptidase activity
(GO:0008233)
Plasma membrane
(GO:0005886)
Proteolysis
(GO:0006508)
Trans-golgi network membrane
(GO:0032588)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Matrix metalloproteinase-24

Genular Protein ID: 4238722157

Symbol: MMP24_MOUSE

Name: Matrix metalloproteinase-24

UniProtKB Accession Codes:

Q9R0S2 A2AUV7 Q9Z0J9

Database IDs:

Citations:

PubMed ID: 10085137

Title: Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP.

PubMed ID: 10085137

DOI: 10.1074/jbc.274.13.8925

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 10622708

Title: Expression, purification and characterization of recombinant mouse MT5-MMP protein products.

PubMed ID: 10622708

DOI: 10.1016/s0014-5793(99)01534-3

PubMed ID: 11470782

Title: Shedding of membrane type matrix metalloproteinase 5 by a furin-type convertase: a potential mechanism for down-regulation.

PubMed ID: 11470782

DOI: 10.1074/jbc.m103680200

PubMed ID: 11714638

Title: Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth.

PubMed ID: 11714638

PubMed ID: 14990567

Title: Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV.

PubMed ID: 14990567

DOI: 10.1074/jbc.m400264200

PubMed ID: 19805319

Title: Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation.

PubMed ID: 19805319

DOI: 10.1073/pnas.0908507106

PubMed ID: 24952463

Title: MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.

PubMed ID: 24952463

DOI: 10.1038/ncb2993

Sequence Information:

Length: 618
Mass: 70460
Checksum: 51C8E61B187264F5
Sequence:

MPRSRGGRAA PGQASRWSGW RAPGRLLPLL PALCCLAAAA GAGKPAGADA PFAGQNWLKS 
YGYLLPYESR ASALHSGKAL QSAVSTMQQF YGIPVTGVLD QTTIEWMKKP RCGVPDHPHL 
SRRRRNKRYA LTGQKWRQKH ITYSIHNYTP KVGELDTRKA IRQAFDVWQK VTPLTFEEVP 
YHEIKSDRKE ADIMIFFASG FHGDSSPFDG EGGFLAHAYF PGPGIGGDTH FDSDEPWTLG 
NANHDGNDLF LVAVHELGHA LGLEHSNDPS AIMAPFYQYM ETHNFKLPQD DLQGIQKIYG 
PPAEPLEPTR PLPTLPVRRI HSPSERKHER HPRPPRPPLG DRPSTPGAKP NICDGNFNTV 
ALFRGEMFVF KDRWFWRLRN NRVQEGYPMQ IEQFWKGLPA RIDAAYERAD GRFVFFKGDK 
YWVFKEVTVE PGYPHSLGEL GSCLPREGID TALRWEPVGK TYFFKGERYW RYSEERRATD 
PGYPKPITVW KGIPQAPQGA FISKEGYYTY FYKGRDYWKF DNQKLSVEPG YPRNILRDWM 
GCKQKEVERR KERRLPQDDV DIMVTIDDVP GSVNAVAVVV PCTLSLCLLV LLYTIFQFKN 
KAGPQPVTYY KRPVQEWV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mmp24

Associated with

Other Information

Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP. PubMed ID: 10085137

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Expression, purification and characterization of recombinant mouse MT5-MMP protein products. PubMed ID: 10622708

Shedding of membrane type matrix metalloproteinase 5 by a furin-type convertase: a potential mechanism for down-regulation. PubMed ID: 11470782

Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth. PubMed ID: 11714638

Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV. PubMed ID: 14990567

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation. PubMed ID: 19805319

MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin. PubMed ID: 24952463