Details for: AFP

Gene ID: 174

Symbol: AFP

Ensembl ID: ENSG00000081051

Description: alpha fetoprotein

Associated with

Other Information

Genular Protein ID: 1586958882

Symbol: FETA_HUMAN

Name: Alpha-fetoprotein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 6192439

Title: Primary structures of human alpha-fetoprotein and its mRNA.

PubMed ID: 6192439

DOI: 10.1073/pnas.80.15.4604

PubMed ID: 2436661

Title: Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene.

PubMed ID: 2436661

DOI: 10.1021/bi00379a020

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2580830

Title: The human alpha-fetoprotein gene. Sequence organization and the 5' flanking region.

PubMed ID: 2580830

DOI: 10.1016/s0021-9258(18)89178-5

PubMed ID: 7684942

Title: A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP).

PubMed ID: 7684942

DOI: 10.1093/hmg/2.4.379

PubMed ID: 6187626

Title: Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA.

PubMed ID: 6187626

DOI: 10.1016/0378-1119(82)90210-4

PubMed ID: 1709810

Title: Human alpha-fetoprotein primary structure: a mass spectrometric study.

PubMed ID: 1709810

DOI: 10.1021/bi00234a032

PubMed ID: 70228

Title: Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis.

PubMed ID: 70228

DOI: 10.1016/0005-2795(77)90198-2

PubMed ID: 71198

Title: Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma.

PubMed ID: 71198

PubMed ID: 4138095

Title: Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury.

PubMed ID: 4138095

PubMed ID: 80265

Title: Copper(II)-binding ability of human alpha-fetoprotein.

PubMed ID: 80265

PubMed ID: 89900

Title: Alpha-fetoprotein as a carrier protein in plasma and its bilirubin-binding ability.

PubMed ID: 89900

PubMed ID: 2414772

Title: Tyrosine sulfation of proteins from the human hepatoma cell line HepG2.

PubMed ID: 2414772

DOI: 10.1073/pnas.82.21.7160

PubMed ID: 15280901

Title: Congenital deficiency of alpha feto-protein.

PubMed ID: 15280901

DOI: 10.1038/sj.ejhg.5201246

PubMed ID: 18854864

Title: A new mutation in the AFP gene responsible for a total absence of alpha feto-protein on second trimester maternal serum screening for Down syndrome.

PubMed ID: 18854864

DOI: 10.1038/ejhg.2008.186

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

Sequence Information:

  • Length: 609
  • Mass: 68678
  • Checksum: 4D4E45820E1C2D4F
  • Sequence:
  • MKWVESIFLI FLLNFTESRT LHRNEYGIAS ILDSYQCTAE ISLADLATIF FAQFVQEATY 
    KEVSKMVKDA LTAIEKPTGD EQSSGCLENQ LPAFLEELCH EKEILEKYGH SDCCSQSEEG 
    RHNCFLAHKK PTPASIPLFQ VPEPVTSCEA YEEDRETFMN KFIYEIARRH PFLYAPTILL 
    WAARYDKIIP SCCKAENAVE CFQTKAATVT KELRESSLLN QHACAVMKNF GTRTFQAITV 
    TKLSQKFTKV NFTEIQKLVL DVAHVHEHCC RGDVLDCLQD GEKIMSYICS QQDTLSNKIT 
    ECCKLTTLER GQCIIHAEND EKPEGLSPNL NRFLGDRDFN QFSSGEKNIF LASFVHEYSR 
    RHPQLAVSVI LRVAKGYQEL LEKCFQTENP LECQDKGEEE LQKYIQESQA LAKRSCGLFQ 
    KLGEYYLQNA FLVAYTKKAP QLTSSELMAI TRKMAATAAT CCQLSEDKLL ACGEGAADII 
    IGHLCIRHEM TPVNPGVGQC CTSSYANRRP CFSSLVVDET YVPPAFSDDK FIFHKDLCQA 
    QGVALQTMKQ EFLINLVKQK PQITEEQLEA VIADFSGLLE KCCQGQEQEV CFAEEGQKLI 
    SKTRAALGV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.