Genular: Defining Cellular Identity and Function

Details for: Mdh2

Gene ID: 17448

Symbol: Mdh2

Ensembl ID: ENSMUSG00000019179

Description: malate dehydrogenase 2, NAD (mitochondrial)

Associated with

Citric acid cycle (tca cycle)
(R-MMU-71403)
Glucose metabolism
(R-MMU-70326)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of proteins
(R-MMU-392499)
Mitochondrial protein degradation
(R-MMU-9837999)
Pyruvate metabolism and citric acid (tca) cycle
(R-MMU-71406)
The citric acid (tca) cycle and respiratory electron transport
(R-MMU-1428517)
Aerobic respiration
(GO:0009060)
Carboxylic acid metabolic process
(GO:0019752)
Catalytic activity
(GO:0003824)
Cytoplasm
(GO:0005737)
Gluconeogenesis
(GO:0006094)
Glyceraldehyde-3-phosphate biosynthetic process
(GO:0046166)
L-malate dehydrogenase activity
(GO:0030060)
Malate dehydrogenase (nadp+) activity
(GO:0046554)
Malate dehydrogenase activity
(GO:0016615)
Malate metabolic process
(GO:0006108)
Membrane
(GO:0016020)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial matrix
(GO:0005759)
Mitochondrion
(GO:0005739)
Myelin sheath
(GO:0043209)
Nadh metabolic process
(GO:0006734)
Oxaloacetate metabolic process
(GO:0006107)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor
(GO:0016616)
Protein self-association
(GO:0043621)
Tricarboxylic acid cycle
(GO:0006099)

Other Information

Proteins

Malate dehydrogenase, mitochondrial

Genular Protein ID: 2675684683

Symbol: MDHM_MOUSE

Name: Malate dehydrogenase, mitochondrial

UniProtKB Accession Codes:

P08249 Q0QF44 Q8CF79 Q8R1P0

Database IDs:

Citations:

PubMed ID: 3038184

Title: Cloning and sequence analysis of cDNAs encoding mammalian mitochondrial malate dehydrogenase.

PubMed ID: 3038184

DOI: 10.1021/bi00383a017

PubMed ID: 3379635

Title: Structural organization of the mouse mitochondrial malate dehydrogenase gene.

PubMed ID: 3379635

DOI: 10.1016/0022-2836(88)90328-2

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16751257

Title: Housekeeping genes for phylogenetic analysis of eutherian relationships.

PubMed ID: 16751257

DOI: 10.1093/molbev/msl027

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

Length: 338
Mass: 35611
Checksum: 99D13BB2099C19F1
Sequence:

MLSALARPAG AALRRSFSTS AQNNAKVAVL GASGGIGQPL SLLLKNSPLV SRLTLYDIAH 
TPGVAADLSH IETRANVKGY LGPEQLPDCL KGCDVVVIPA GVPRKPGMTR DDLFNTNATI 
VATLTAACAQ HCPEAMVCII ANPVNSTIPI TAEVFKKHGV YNPNKIFGVT TLDIVRANTF 
VAELKGLDPA RVNVPVIGGH AGKTIIPLIS QCTPKVDFPQ DQLATLTGRI QEAGTEVVKA 
KAGAGSATLS MAYAGARFVF SLVDAMNGKE GVVECSFVQS KETECTYFST PLLLGKKGLE 
KNLGIGKITP FEEKMIAEAI PELKASIKKG EDFVKNMK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mdh2

Associated with

Other Information

Cloning and sequence analysis of cDNAs encoding mammalian mitochondrial malate dehydrogenase. PubMed ID: 3038184

Structural organization of the mouse mitochondrial malate dehydrogenase gene. PubMed ID: 3379635

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Housekeeping genes for phylogenetic analysis of eutherian relationships. PubMed ID: 16751257

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753