Genular: Defining Cellular Identity and Function

Details for: Msi1

Gene ID: 17690

Symbol: Msi1

Ensembl ID: ENSMUSG00000054256

Description: musashi RNA-binding protein 1

Associated with

Central nervous system development
(GO:0007417)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Identical protein binding
(GO:0042802)
Mrna binding
(GO:0003729)
Nucleic acid binding
(GO:0003676)
Nucleus
(GO:0005634)
Poly(u) rna binding
(GO:0008266)
Regulation of translation
(GO:0006417)
Response to hormone
(GO:0009725)
Rna binding
(GO:0003723)
Single-stranded rna binding
(GO:0003727)

Other Information

Proteins

RNA-binding protein Musashi homolog 1

Genular Protein ID: 1050505135

Symbol: MSI1H_MOUSE

Name: RNA-binding protein Musashi homolog 1

UniProtKB Accession Codes:

Q61474 Q8BNC7

Database IDs:

Citations:

PubMed ID: 8660864

Title: Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell.

PubMed ID: 8660864

DOI: 10.1006/dbio.1996.0130

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 11359897

Title: The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA.

PubMed ID: 11359897

DOI: 10.1128/mcb.21.12.3888-3900.2001

PubMed ID: 12407178

Title: RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.

PubMed ID: 12407178

DOI: 10.1073/pnas.232087499

PubMed ID: 16554442

Title: A role for the ELAV RNA-binding proteins in neural stem cells: stabilization of Msi1 mRNA.

PubMed ID: 16554442

DOI: 10.1242/jcs.02852

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 10080895

Title: Structure, backbone dynamics and interactions with RNA of the C-terminal RNA-binding domain of a mouse neural RNA-binding protein, Musashi1.

PubMed ID: 10080895

DOI: 10.1006/jmbi.1999.2596

PubMed ID: 12907678

Title: Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics.

PubMed ID: 12907678

DOI: 10.1074/jbc.m306210200

Sequence Information:

Length: 362
Mass: 39119
Checksum: 75C316BB384AE211
Sequence:

METDAPQPGL ASPDSPHDPC KMFIGGLSWQ TTQEGLREYF GQFGEVKECL VMRDPLTKRS 
RGFGFVTFMD QAGVDKVLAQ SRHELDSKTI DPKVAFPRRA QPKMVTRTKK IFVGGLSVNT 
TVEDVKHYFE QFGKVDDAML MFDKTTNRHR GFGFVTFESE DIVEKVCEIH FHEINNKMVE 
CKKAQPKEVM SPTGSARGRS RVMPYGMDAF MLGIGMLGYP GFQATTYASR SYTGLAPGYT 
YQFPEFRVER SPLPSAPVLP ELTAIPLTAY GPMAAAAAAA AVVRGTGSHP WTMAPPPGST 
PSRTGGFLGT TSPGPMAELY GAANQDSGVS SYISAASPAP STGFGHSLGG PLIATAFTNG 
YH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Msi1

Associated with

Other Information

Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell. PubMed ID: 8660864

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA. PubMed ID: 11359897

RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation. PubMed ID: 12407178

A role for the ELAV RNA-binding proteins in neural stem cells: stabilization of Msi1 mRNA. PubMed ID: 16554442

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Structure, backbone dynamics and interactions with RNA of the C-terminal RNA-binding domain of a mouse neural RNA-binding protein, Musashi1. PubMed ID: 10080895

Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics. PubMed ID: 12907678