Details for: Msn

Gene ID: 17698

Symbol: Msn

Ensembl ID: ENSMUSG00000031207

Description: moesin

Associated with

Other Information

Genular Protein ID: 567353583

Symbol: MOES_MOUSE

Name: Membrane-organizing extension spike protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1429901

Title: A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.

PubMed ID: 1429901

DOI: 10.1242/jcs.103.1.131

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1573844

Title: Moesin, a new cytoskeletal protein and constituent of filopodia: its role in cellular functions.

PubMed ID: 1573844

DOI: 10.1038/ki.1992.102

PubMed ID: 9856983

Title: Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures.

PubMed ID: 9856983

DOI: 10.1074/jbc.273.52.34663

PubMed ID: 9456324

Title: Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association.

PubMed ID: 9456324

DOI: 10.1083/jcb.140.3.647

PubMed ID: 9472040

Title: Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.

PubMed ID: 9472040

DOI: 10.1083/jcb.140.4.885

PubMed ID: 9890997

Title: Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.

PubMed ID: 9890997

DOI: 10.1074/jbc.274.4.2315

PubMed ID: 11777944

Title: Negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly.

PubMed ID: 11777944

DOI: 10.4049/jimmunol.168.2.541

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22875842

Title: Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis.

PubMed ID: 22875842

DOI: 10.1093/intimm/dxs077

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 28978692

Title: The ERM Protein Moesin Regulates CD8+ Regulatory T Cell Homeostasis and Self-Tolerance.

PubMed ID: 28978692

DOI: 10.4049/jimmunol.1700074

PubMed ID: 29247647

Title: Moesin and myosin IIA modulate phagolysosomal biogenesis in macrophages.

PubMed ID: 29247647

DOI: 10.1016/j.bbrc.2017.12.061

Sequence Information:

  • Length: 577
  • Mass: 67767
  • Checksum: 4E9B5521313EF5B5
  • Sequence:
  • MPKTISVRVT TMDAELEFAI QPNTTGKQLF DQVVKTIGLR EVWFFGLQYQ DTKAFSTWLK 
    LNKKVTAQDV RKESPLLFKF RAKFYPEDVS EELIQDITQR LFFLQVKEGI LNDDIYCPPE 
    TAVLLASYAV QSKYGDFNKE VHKSGYLAGD KLLPQRVLEQ HKLNKDQWEE RIQVWHEEHR 
    GMLREDAVLE YLKIAQDLEM YGVNYFSIKN KKGSELWLGV DALGLNIYEQ NDRLTPKIGF 
    PWSEIRNISF NDKKFVIKPI DKKAPDFVFY APRLRINKRI LALCMGNHEL YMRRRKPDTI 
    EVQQMKAQAR EEKHQKQMER ALLENEKKKR ELAEKEKEKI EREKEELMEK LKQIEEQTKK 
    AQQELEEQTR RALELEQERK RAQSEAEKLA KERQEAEEAK EALLQASRDQ KKTQEQLASE 
    MAELTARISQ LEMARKKKES EAVEWQQKAQ MVQEDLEKTR AELKTAMSTP HVAEPAENEH 
    DEQDENGAEA SAELRADAMA KDRSEEERTT EAEKNERVQK HLKALTSELA NARDESKKTA 
    NDMIHAENMR LGRDKYKTLR QIRQGNTKQR IDEFESM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.