Details for: Nudt1

Gene ID: 17766

Symbol: Nudt1

Ensembl ID: ENSMUSG00000036639

Description: nudix hydrolase 1

Associated with

Other Information

Genular Protein ID: 2964948061

Symbol: 8ODP_MOUSE

Name: 2-hydroxy-dATP diphosphatase

UniProtKB Accession Codes:

P53368 P97795 Q542J4 Q8VDG0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 53 ChiTaRS 1 DNASU 1 EC 1 EMBL 9 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 23 Gene3D 1 GeneTree 1 Genevisible 1 InParanoid 1 InterPro 5 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PDB 8 PDBsum 3 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 Rhea 14 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 7592783

Title: Mouse MTH1 protein with 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphatase activity that prevents transversion mutation. cDNA cloning and tissue distribution.

PubMed ID: 7592783

DOI: 10.1074/jbc.270.43.25942

PubMed ID: 9013634

Title: Organization and expression of the mouse MTH1 gene for preventing transversion mutation.

PubMed ID: 9013634

DOI: 10.1074/jbc.272.6.3766

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11572992

Title: Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase.

PubMed ID: 11572992

DOI: 10.1073/pnas.191086798

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 30304478

Title: MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP.

PubMed ID: 30304478

DOI: 10.1093/nar/gky896

PubMed ID: 32144205

Title: MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.

PubMed ID: 32144205

DOI: 10.1074/jbc.ra120.012636

PubMed ID: 29281266

Title: Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity.

PubMed ID: 29281266

DOI: 10.1021/acs.biochem.7b01163

Sequence Information:

  • Length: 156
  • Mass: 17908
  • Checksum: 9E6C12EC2A6DE4B7
  • Sequence:
    • MSTSRLYTLV LVLQPQRVLL GMKKRGFGAG RWNGFGGKVQ EGETIEDGAK RELLEESGLS 
VDTLHKVGHI SFEFVGSPEL MDVHIFSADH VHGTPTESEE MRPQWFQLDQ IPFADLWPDD 
SYWFPLLLQK KKFCGHFKFQ DQDTILSYSL REVDSF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.