Details for: Mttp

Gene ID: 17777

Symbol: Mttp

Ensembl ID: ENSMUSG00000028158

Description: microsomal triglyceride transfer protein

Associated with

Other Information

Genular Protein ID: 1352336718

Symbol: MTP_MOUSE

Name: Microsomal triglyceride transfer protein large subunit

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8660984

Title: Mouse microsomal triglyceride transfer protein large subunit: cDNA cloning, tissue-specific expression and chromosomal localization.

PubMed ID: 8660984

DOI: 10.1006/geno.1996.0200

PubMed ID: 17312007

Title: MTP regulated by an alternate promoter is essential for NKT cell development.

PubMed ID: 17312007

DOI: 10.1084/jem.20062006

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9502759

Title: Apo B100-containing lipoproteins are secreted by the heart.

PubMed ID: 9502759

DOI: 10.1172/jci1785

PubMed ID: 10713055

Title: A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion.

PubMed ID: 10713055

DOI: 10.1074/jbc.275.11.7515

PubMed ID: 10744773

Title: Microsomal triglyceride transfer protein expression during mouse development.

PubMed ID: 10744773

PubMed ID: 15897609

Title: Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein.

PubMed ID: 15897609

DOI: 10.1194/jlr.d400043-jlr200

PubMed ID: 16478722

Title: Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and secretion of apolipoprotein B lipoproteins.

PubMed ID: 16478722

DOI: 10.1074/jbc.m512823200

PubMed ID: 17635917

Title: Identification of a novel isoform of microsomal triglyceride transfer protein.

PubMed ID: 17635917

DOI: 10.1074/jbc.m700500200

PubMed ID: 18502767

Title: Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition.

PubMed ID: 18502767

DOI: 10.1074/jbc.m800398200

PubMed ID: 18497885

Title: FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice.

PubMed ID: 18497885

DOI: 10.1172/jci32914

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24353284

Title: LGR4 acts as a link between the peripheral circadian clock and lipid metabolism in liver.

PubMed ID: 24353284

DOI: 10.1530/jme-13-0042

PubMed ID: 33168624

Title: PRAP1 is a novel lipid-binding protein that promotes lipid absorption by facilitating MTTP-mediated lipid transport.

PubMed ID: 33168624

DOI: 10.1074/jbc.ra120.015002

Sequence Information:

  • Length: 894
  • Mass: 99099
  • Checksum: 3D8E5EB470CAA6FC
  • Sequence:
  • MILLAVLFLC FFSSYSASVK GHTTGLSLNN ERLYKLTYST EVFLDGGKGK PQDSVGYKIS 
    SDVDVVLLWR NPDGDDDQVI QVTITAVNVE NAGQQRGEKS IFQGKSTPKI IGKDNLEALQ 
    RPMLLHLVRG KVKEFYSYEN EPVGIENLKR GLASLFQMQL SSGTTNEVDI SGDCKVTYQA 
    QQDKVVKIKA LDTCKIERSG FTTANQVLGV SSKATSVTTY KIEDSFVTAV LAEETRAFAL 
    NFQQTIAGKI VSKQKLELKT TEAGPRMIPG KQVAGVIKAV DSKYKAIPIV GQVLERVCKG 
    CPSLAEHWKS IRKNLEPENL SKAEAVQSFL AFIQHLRTSR REEILQILKA EKKEVLPQLV 
    DAVTSAQTPD SLEAILDFLD FKSDSSIILQ ERFLYACGFA THPDEELLRA LLSKFKGSFA 
    SNDIRESVMI IIGALVRKLC QNEGCKLKAV VEAKKLILGG LEKPEKKEDT TMYLLALKNA 
    LLPEGIPLLL KYAEAGEGPV SHLATTVLQR YDVSFITDEV KKTLNRIYHQ NRKVHEKTVR 
    TTAAAVILKN PSYMDVKNIL LSIGELPKEM NKYMLTVVQD ILHFEMPASK MIRRVLKEMA 
    VHNYDRFSKS GSSSAYTGYV ERSPRAASTY SLDILYSGSG ILRRSNLNIF QYIGKAELHG 
    SQVVIEAQGL EGLIAATPDE GEENLDSYAG MSAILFDVQL RPVTFFNGYS DLMSKMLSAS 
    GDPVSVVKGL ILLIDHSQDI QLQSGLKANM EIQGGLAIDI SGSMEFSLWY RESKTRVKNR 
    VAVVITSDVT VDASFVKAGV ESRAETEAGL EFISTVQFSQ YPFLVCMQMD KAEAPLRQFE 
    TKYERLSTGR GYVSRRRKES LVAGCELPLH QENSEMCNVV FPPQPESDNS GGWF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.