Details for: Mxi1

Gene ID: 17859

Symbol: Mxi1

Ensembl ID: ENSMUSG00000025025

Description: MAX interactor 1, dimerization protein

Associated with

  • Blastocyst formation
    (GO:0001825)
  • Cytosol
    (GO:0005829)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleolus
    (GO:0005730)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Protein dimerization activity
    (GO:0046983)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)

Other Information

Genular Protein ID: 1836778718

Symbol: MXI1_MOUSE

Name: Max-interacting protein 1

UniProtKB Accession Codes:

P50540

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 5 Ensembl 5 ExpressionAtlas 1 GO 12 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 5 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 7889571

Title: An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3.

PubMed ID: 7889571

DOI: 10.1016/0092-8674(95)90356-9

PubMed ID: 7954804

Title: Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites.

PubMed ID: 7954804

PubMed ID: 7835718

Title: Cloning and sequencing of the murine Mxi1 cDNA.

PubMed ID: 7835718

DOI: 10.1016/0378-1119(94)00722-5

PubMed ID: 8521822

Title: Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.

PubMed ID: 8521822

DOI: 10.1002/j.1460-2075.1995.tb00252.x

PubMed ID: 8617250

Title:

PubMed ID: 8617250

DOI: 10.1002/j.1460-2075.1996.tb00555.x

PubMed ID: 9528857

Title: Mmip1: a novel leucine zipper protein that reverses the suppressive effects of mad family members on C-myc.

PubMed ID: 9528857

DOI: 10.1038/sj.onc.1201634

PubMed ID: 10597267

Title: Mmip-2, a novel RING finger protein that interacts with mad members of the Myc oncoprotein network.

PubMed ID: 10597267

DOI: 10.1038/sj.onc.1203097

Sequence Information:

  • Length: 228
  • Mass: 25978
  • Checksum: 7B5D4ACAEF97C4F1
  • Sequence:
    • MERVRMINVQ RLLEAAEFLE RRERECEHGY ASSFPSMPSP RLQHSKPPRR LSRAQKHSSG 
SSNTSTANRS THNELEKNRR AHLRLCLERL KVLIPLGPDC TRHTTLGLLN KAKAHIKKLE 
EAERKSQHQL ENLEREQRFL KRRLEQLQGP QEMERIRMDS IGSTISSDRS DSEREEIEVD 
VESTEFSHGE ADSVSTTSIS DLDDHSSLQS VGSDEGYSSA SVKLSFAS

Genular Protein ID: 455366320

Symbol: Q3U3X2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3U3X2

Database IDs:

AGR 1 ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 HOGENOM 1 InterPro 2 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 295
  • Mass: 32797
  • Checksum: F2EE225A7F6A3356
  • Sequence:
    • MGKRGRPRKE ARCEGAGLVP VAPPAMPPAA AAPQPPAQPE EPAGAKPRCP FSDIFNTSEN 
SMEKHINTFL QNVQILLEAA SYLEQIEKEN KKCEHGYASS FPSMPSPRLQ HSKPPRRLSR 
AQKHSSGSSN TSTANRSTHN ELEKNRRAHL RLCLERLKVL IPLGPDCTRH TTLGLLNKAK 
AHIKKLEEAE RKSQHQLENL EREQRFLKRR LEQLQGPQEM ERIRMDSIGS TISSDRSDSE 
REEIEVDVES TEFSHGEADS VSTTSISDLD DHSSLQSVGS DEGYSSASVK LSFAS

Genular Protein ID: 2628386832

Symbol: Q6P2L3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q6P2L3

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 Genevisible 1 InterPro 2 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 270
  • Mass: 30211
  • Checksum: 4F46C20EC48C3B66
  • Sequence:
    • MPPAAAAPQP PAQPEEPAGA KPRCPFSDIF NTSENSMEKH INTFLQNVQI LLEAASYLEQ 
IEKENKKCEH GYASSFPSMP SPRLQHSKPP RRLSRAQKHS SGSSNTSTAN RSTHNELEKN 
RRAHLRLCLE RLKVLIPLGP DCTRHTTLGL LNKAKAHIKK LEEAERKSQH QLENLEREQR 
FLKRRLEQLQ GPQEMERIRM DSIGSTISSD RSDSEREEIE VDVESTEFSH GEADSVSTTS 
ISDLDDHSSL QSVGSDEGYS SASVKLSFAS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.