Genular: Defining Cellular Identity and Function

Details for: Myh6

Gene ID: 17888

Symbol: Myh6

Ensembl ID: ENSMUSG00000040752

Description: myosin, heavy polypeptide 6, cardiac muscle, alpha

Associated with

Actin binding
(GO:0003779)
Actin filament-based movement
(GO:0030048)
Actin filament binding
(GO:0051015)
Adult heart development
(GO:0007512)
Atp binding
(GO:0005524)
Atp metabolic process
(GO:0046034)
Atrial cardiac muscle tissue morphogenesis
(GO:0055009)
Calcium-dependent atpase activity
(GO:0030899)
Calmodulin binding
(GO:0005516)
Cardiac muscle cell development
(GO:0055013)
Cardiac muscle contraction
(GO:0060048)
Cardiac muscle hypertrophy in response to stress
(GO:0014898)
Cytoplasm
(GO:0005737)
Cytoskeletal motor activity
(GO:0003774)
Identical protein binding
(GO:0042802)
In utero embryonic development
(GO:0001701)
Microfilament motor activity
(GO:0000146)
Muscle contraction
(GO:0006936)
Muscle filament sliding
(GO:0030049)
Muscle myosin complex
(GO:0005859)
Myofibril
(GO:0030016)
Myofibril assembly
(GO:0030239)
Myosin complex
(GO:0016459)
Myosin filament
(GO:0032982)
Myosin ii complex
(GO:0016460)
Nucleotide binding
(GO:0000166)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Regulation of atp-dependent activity
(GO:0043462)
Regulation of blood pressure
(GO:0008217)
Regulation of heart contraction
(GO:0008016)
Regulation of heart growth
(GO:0060420)
Regulation of heart rate
(GO:0002027)
Regulation of the force of heart contraction
(GO:0002026)
Sarcomere organization
(GO:0045214)
Stress fiber
(GO:0001725)
Striated muscle contraction
(GO:0006941)
Ventricular cardiac muscle tissue morphogenesis
(GO:0055010)
Visceral muscle development
(GO:0007522)
Z disc
(GO:0030018)

Other Information

Proteins

Myosin-6

Genular Protein ID: 3950203291

Symbol: MYH6_MOUSE

Name: Myosin-6

UniProtKB Accession Codes:

Q02566 Q64258 Q64738

Database IDs:

Citations:

PubMed ID: 1577481

Title: Characterization of the allelic differences in the mouse cardiac alpha-myosin heavy chain coding sequence.

PubMed ID: 1577481

DOI: 10.1016/0888-7543(92)90218-h

PubMed ID: 2026617

Title: Isolation and characterization of the mouse cardiac myosin heavy chain genes.

PubMed ID: 2026617

DOI: 10.1016/s0021-9258(18)31568-0

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1938
Mass: 223565
Checksum: EAD789ADA68818FB
Sequence:

MTDAQMADFG AAAQYLRKSE KERLEAQTRP FDIRTECFVP DDKEEYVKAK VVSREGGKVT 
AETENGKTVT IKEDQVMQQN PPKFDKIEDM AMLTFLHEPA VLYNLKERYA AWMIYTYSGL 
FCVTVNPYKW LPVYNAEVVA AYRGKKRSEA PPHIFSISDN AYQYMLTDRE NQSILITGES 
GAGKTVNTKR VIQYFASIAA IGDRSKKENP NANKGTLEDQ IIQANPALEA FGNAKTVRND 
NSSRFGKFIR IHFGATGKLA SADIETYLLE KSRVIFQLKA ERNYHIFYQI LSNKKPELLD 
MLLVTNNPYD YAFVSQGEVS VASIDDSEEL LATDSAFDVL SFTAEEKAGV YKLTGAIMHY 
GNMKFKQKQR EEQAEPDGTE DADKSAYLMG LNSADLLKGL CHPRVKVGNE YVTKGQSVQQ 
VYYSIGALAK SVYEKMFNWM VTRINATLET KQPRQYFIGV LDIAGFEIFD FNSFEQLCIN 
FTNEKLQQFF NHHMFVLEQE EYKKEGIEWE FIDFGMDLQA CIDLIEKPMG IMSILEEECM 
FPKASDMTFK AKLYDNHLGK SNNFQKPRNV KGKQEAHFSL VHYAGTVDYN IMGWLEKNKD 
PLNETVVGLY QKSSLKLMAT LFSTYASADT GDSGKGKGGK KKGSSFQTVS ALHRENLNKL 
MTNLKTTHPH FVRCIIPNER KAPGVMDNPL VMHQLRCNGV LEGIRICRKG FPNRILYGDF 
RQRYRILNPA AIPEGQFIDS RKGAEKLLGS LDIDHNQYKF GHTKVFFKAG LLGLLEEMRD 
ERLSRIITRI QAQARGQLMR IEFKKIVERR DALLVIQWNI RAFMGVKNWP WMKLYFKIKP 
LLKSAETEKE MANMKEEFGR VKDALEKSEA RRKELEEKMV SLLQEKNDLQ LQVQAEQDNL 
NDAEERCDQL IKNKIQLEAK VKEMTERLED EEEMNAELTA KKRKLEDECS ELKKDIDDLE 
LTLAKVEKEK HATENKVKNL TEEMAGLDEI IAKLTKEKKA LQEAHQQALD DLQAEEDKVN 
TLTKSKVKLE QQVDDLEGSL EQEKKVRMDL ERAKRKLEGD LKLTQESIMD LENDKLQLEE 
KLKKKEFDIS QQNSKIEDEQ ALALQLQKKL KENQARIEEL EEELEAERTA RAKVEKLRSD 
LSRELEEISE RLEEAGGATS VQIEMNKKRE AEFQKMRRDL EEATLQHEAT AAALRKKHAD 
SVAELGEQID NLQRVKQKLE KEKSEFKLEL DDVTSNMEQI IKAKANLEKV SRTLEDQANE 
YRVKLEEAQR SLNDFTTQRA KLQTENGELA RQLEEKEALI SQLTRGKLSY TQQMEDLKRQ 
LEEEGKAKNA LAHALQSSRH DCDLLREQYE EEMEAKAELQ RVLSKANSEV AQWRTKYETD 
AIQRTEELEE AKKKLAQRLQ DAEEAVEAVN AKCSSLEKTK HRLQNEIEDL MVDVERSNAA 
AAALDKKQRN FDKILAEWKQ KYEESQSELE SSQKEARSLS TELFKLKNAY EESLEHLETF 
KRENKNLQEE ISDLTEQLGE GGKNVHELEK IRKQLEVEKL ELQSALEEAE ASLEHEEGKI 
LRAQLEFNQI KAEIERKLAE KDEEMEQAKR NHLRMVDSLQ TSLDAETRSR NEALRVKKKM 
EGDLNEMEIQ LSQANRIASE AQKHLKNSQA HLKDTQLQLD DAVHANDDLK ENIAIVERRN 
NLLQAELEEL RAVVEQTERS RKLAEQELIE TSERVQLLHS QNTSLINQKK KMESDLTQLQ 
TEVEEAVQEC RNAEEKAKKA ITDAAMMAEE LKKEQDTSAH LERMKKNMEQ TIKDLQHRLD 
EAEQIALKGG KKQLQKLEAR VRELENELEA EQKRNAESVK GMRKSERRIK ELTYQTEEDK 
KNLMRLQDLV DKLQLKVKAY KRQAEEAEEQ ANTNLSKFRK VQHELDEAEE RADIAESQVN 
KLRAKSRDIG AKKMHDEE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.