Genular: Defining Cellular Identity and Function

Details for: Ncf1

Gene ID: 17969

Symbol: Ncf1

Ensembl ID: ENSMUSG00000015950

Description: neutrophil cytosolic factor 1

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing-cross presentation
(R-MMU-1236975)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Cross-presentation of particulate exogenous antigens (phagosomes)
(R-MMU-1236973)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Rho gtpase cycle
(R-MMU-9012999)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate nadph oxidases
(R-MMU-5668599)
Ros and rns production in phagocytes
(R-MMU-1222556)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Cellular defense response
(GO:0006968)
Cytoplasm
(GO:0005737)
Cytoplasmic side of plasma membrane
(GO:0009898)
Cytosol
(GO:0005829)
Defense response to bacterium
(GO:0042742)
Defense response to fungus
(GO:0050832)
Defense response to gram-positive bacterium
(GO:0050830)
Dendrite
(GO:0030425)
Epithelial cell proliferation
(GO:0050673)
Hydrogen peroxide biosynthetic process
(GO:0050665)
Inflammatory response
(GO:0006954)
Leukocyte mediated cytotoxicity
(GO:0001909)
Leukotriene metabolic process
(GO:0006691)
Lipid binding
(GO:0008289)
Membrane
(GO:0016020)
Nadp catabolic process
(GO:0006742)
Nadph oxidase complex
(GO:0043020)
Negative regulation of smooth muscle contraction
(GO:0045986)
Neuronal cell body
(GO:0043025)
Neutrophil-mediated killing of fungus
(GO:0070947)
Neutrophil-mediated killing of gram-positive bacterium
(GO:0070946)
Phosphatidylinositol-3,4-bisphosphate binding
(GO:0043325)
Phosphatidylinositol binding
(GO:0035091)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Reactive oxygen species biosynthetic process
(GO:1903409)
Regulation of respiratory burst involved in inflammatory response
(GO:0060264)
Respiratory burst
(GO:0045730)
Respiratory burst involved in defense response
(GO:0002679)
Response to bacterium
(GO:0009617)
Response to yeast
(GO:0001878)
Sh3 domain binding
(GO:0017124)
Smooth muscle contraction
(GO:0006939)
Superoxide-generating nad(p)h oxidase activity
(GO:0016175)
Superoxide-generating nadph oxidase activator activity
(GO:0016176)
Superoxide anion generation
(GO:0042554)

Other Information

Proteins

Genular Protein ID: 958661229

Symbol: NCF1_MOUSE

Name: Neutrophil cytosol factor 1

UniProtKB Accession Codes:

Q09014 O70144 Q3UE58 Q9JI34

Database IDs:

Citations:

PubMed ID: 8119734

Title: Cloning and functional expression of the mouse homologue of p47phox.

PubMed ID: 8119734

DOI: 10.1007/bf00188790

PubMed ID: 9490028

Title: Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex.

PubMed ID: 9490028

DOI: 10.1046/j.1432-1327.1998.2510573.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 16814099

Title: Noxa1 is a central component of the smooth muscle NADPH oxidase in mice.

PubMed ID: 16814099

DOI: 10.1016/j.freeradbiomed.2005.12.035

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26021615

Title: Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis.

PubMed ID: 26021615

DOI: 10.1038/cr.2015.63

Sequence Information:

Length: 390
Mass: 44667
Checksum: C8EFAB953839CE9A
Sequence:

MGDTFIRHIA LLGFEKRFIP SQHYVYMFLV KWQDLSEKVV YRKFTEIYEF HKMLKEMFPI 
EAGEIHTENR VIPHLPAPRW FDGQRAAESR QGTLTEYFNG LMGLPVKISR CPHLLDFFKV 
RPDDLKLPTD SQAKKPETYL VPKDGKNNVA DITGPIILQT YRAIADYEKS SGTEMTVATG 
DVVDVVEKSE SGWWFCQMKT KRGWVPASYL EPLDSPDEAE DPDPNYAGEP YVTIKAYAAV 
EEDEMSLSEG EAIEVIHKLL DGWWVVRKGD ITGYFPSMYL QKAGEEITQA QRQIRGRGAP 
PRRSTIRNAQ SIHQRSRKRL SQDTYRRNSV RFLQQRRRPG RPGPLSTDGT KDNPSTPRVK 
PQPAVPPRPS SDLILHRCTE STKRKLTSAV

Genular Protein ID: 1709276442

Symbol: Q3UBI5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UBI5

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 404
Mass: 45987
Checksum: 18B9804285C4F1FE
Sequence:

MGDTFIRHIA LLGFEKRFIP SQHYVYMFLV KWQDLSEKVV YKKFTEIYEF HKMLKEMFPI 
EAGEIHTENR VIPHLPAPRW FDGQRAAESR QGTLTEYFNG LMGLPVKISR CPHLLDFFKV 
RPDDLKLPTD SQAKKPETYL VPKDGKNNVA DITGPIILQT YRAIADYEKS SGTEMTVATG 
DVVDVVEKSE SGWWFCQMKT KRGWVPASYL EPLDSPDEAE DPDPNYAGEP YVTIKAYAAV 
EEDEMSLSEG EAIEVIHKLL DGWWVVRKGD ITGYFPSMYL QKAGEEITQA QRQIRGRGAP 
PRRSTIRNAQ SIHQRSRKRL SQDTYRRNSV RFLQQRRRPG RPGPLSTDGT KGERQGGPGP 
GLEGRDNPST PRVKPQPAVP PRPSSDLILH RCTESTKRKL TSAV

Genular Protein ID: 2519201766

Symbol: F8WH69_MOUSE

Name: N/A

UniProtKB Accession Codes:

F8WH69

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 404
Mass: 46015
Checksum: 03DCD67808332952
Sequence:

MGDTFIRHIA LLGFEKRFIP SQHYVYMFLV KWQDLSEKVV YRKFTEIYEF HKMLKEMFPI 
EAGEIHTENR VIPHLPAPRW FDGQRAAESR QGTLTEYFNG LMGLPVKISR CPHLLDFFKV 
RPDDLKLPTD SQAKKPETYL VPKDGKNNVA DITGPIILQT YRAIADYEKS SGTEMTVATG 
DVVDVVEKSE SGWWFCQMKT KRGWVPASYL EPLDSPDEAE DPDPNYAGEP YVTIKAYAAV 
EEDEMSLSEG EAIEVIHKLL DGWWVVRKGD ITGYFPSMYL QKAGEEITQA QRQIRGRGAP 
PRRSTIRNAQ SIHQRSRKRL SQDTYRRNSV RFLQQRRRPG RPGPLSTDGT KGERQGGPGP 
GLEGRDNPST PRVKPQPAVP PRPSSDLILH RCTESTKRKL TSAV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ncf1

Associated with

Other Information

Cloning and functional expression of the mouse homologue of p47phox. PubMed ID: 8119734

Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex. PubMed ID: 9490028

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Noxa1 is a central component of the smooth muscle NADPH oxidase in mice. PubMed ID: 16814099

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis. PubMed ID: 26021615

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 8119734

PubMed ID: 9490028

PubMed ID: 16141072

PubMed ID: 16814099

PubMed ID: 21183079

PubMed ID: 26021615

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 16141073

PubMed ID: 19468303

PubMed ID: 21183079