Genular: Defining Cellular Identity and Function

Details for: Ncf2

Gene ID: 17970

Symbol: Ncf2

Ensembl ID: ENSMUSG00000026480

Description: neutrophil cytosolic factor 2

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing-cross presentation
(R-MMU-1236975)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Cross-presentation of particulate exogenous antigens (phagosomes)
(R-MMU-1236973)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Rho gtpase cycle
(R-MMU-9012999)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate nadph oxidases
(R-MMU-5668599)
Ros and rns production in phagocytes
(R-MMU-1222556)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Acrosomal vesicle
(GO:0001669)
Cellular response to hormone stimulus
(GO:0032870)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Membrane
(GO:0016020)
Nadp catabolic process
(GO:0006742)
Nadph oxidase complex
(GO:0043020)
Phagocytosis
(GO:0006909)
Positive regulation of blood pressure
(GO:0045777)
Positive regulation of neuron apoptotic process
(GO:0043525)
Protein binding
(GO:0005515)
Regulation of reactive oxygen species biosynthetic process
(GO:1903426)
Respiratory burst
(GO:0045730)
Response to glucose
(GO:0009749)
Response to lipopolysaccharide
(GO:0032496)
Response to organic cyclic compound
(GO:0014070)
Small gtpase binding
(GO:0031267)
Superoxide-generating nad(p)h oxidase activity
(GO:0016175)
Superoxide-generating nadph oxidase activator activity
(GO:0016176)
Superoxide anion generation
(GO:0042554)
Superoxide metabolic process
(GO:0006801)

Other Information

Proteins

Neutrophil cytosol factor 2

Genular Protein ID: 1361313923

Symbol: NCF2_MOUSE

Name: Neutrophil cytosol factor 2

UniProtKB Accession Codes:

O70145 Q3TC92 Q3U5S4

Database IDs:

Citations:

PubMed ID: 9490028

Title: Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex.

PubMed ID: 9490028

DOI: 10.1046/j.1432-1327.1998.2510573.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21551061

Title: A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection.

PubMed ID: 21551061

DOI: 10.1126/science.1201711

Sequence Information:

Length: 525
Mass: 59485
Checksum: 663DB6B52D790F76
Sequence:

MSLAEAIRLW NEGVLAADKK DWKGALEAFS EVQDPHSRIC FNIGCVNTIL ENLQAAEQAF 
TKSINRDKHS AVAYFQRGML YYRMEKYDLA IKDLKEALTQ LRGNQLIDYK ILGLQFKLFA 
CEVLYNIALM HAKKEEWKKA EEQLALATNM KSEPRHSKID KAMESIWKQK LFEPVVIPVG 
RLFRPNERQV AQLAKKDYLG KATVVASVVH QDNFSGFAPL QPQSAEPPPR PKTPEIFRAL 
EGEAHRVLFG FVPETPEELQ VMPGNIVFVL KKGSDNWATV MFNGQKGLVP CNYLEPVELR 
IHPQSQPQED TSPESDIPPP PNSSPPGRLQ LSPGHKQKEP KELKLSVPMP YMLKVHYKYT 
VVMETRLGLP YSQLRNMVSK KLALSPEHTK LSYRRRDSHE LLLLSEESMK DAWGQVKNYC 
LTLWCEHTVG DQGLIDEPIQ RENSDASKQT TEPQPKEGTQ VVAIFSYEAA QPEDLEFVEG 
DVILVLSHVN EEWLEGECKG KVGIFPKAFV EGCAAKNLEG IPREV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ncf2

Associated with

Other Information

Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex. PubMed ID: 9490028

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079