Genular: Defining Cellular Identity and Function

Details for: Ncf4

Gene ID: 17972

Symbol: Ncf4

Ensembl ID: ENSMUSG00000071715

Description: neutrophil cytosolic factor 4

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing-cross presentation
(R-MMU-1236975)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Cross-presentation of particulate exogenous antigens (phagosomes)
(R-MMU-1236973)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Rho gtpase cycle
(R-MMU-9012999)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate nadph oxidases
(R-MMU-5668599)
Ros and rns production in phagocytes
(R-MMU-1222556)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Endosome
(GO:0005768)
Endosome membrane
(GO:0010008)
Lipid binding
(GO:0008289)
Membrane
(GO:0016020)
Nadph oxidase complex
(GO:0043020)
Phagocytosis
(GO:0006909)
Phosphatidylinositol-3-phosphate binding
(GO:0032266)
Phosphatidylinositol binding
(GO:0035091)
Protein binding
(GO:0005515)
Respiratory burst
(GO:0045730)
Superoxide-generating nadph oxidase activator activity
(GO:0016176)
Superoxide anion generation
(GO:0042554)

Other Information

Proteins

Neutrophil cytosol factor 4

Genular Protein ID: 207832433

Symbol: NCF4_MOUSE

Name: Neutrophil cytosol factor 4

UniProtKB Accession Codes:

P97369 Q3TBC6

Database IDs:

Citations:

PubMed ID: 8995189

Title: Cloning and chromosomal localization of ncf4, the mouse homologue of p40-phox.

PubMed ID: 8995189

DOI: 10.1007/s002510050192

PubMed ID: 9490028

Title: Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex.

PubMed ID: 9490028

DOI: 10.1046/j.1432-1327.1998.2510573.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21551061

Title: A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection.

PubMed ID: 21551061

DOI: 10.1126/science.1201711

Sequence Information:

Length: 339
Mass: 38707
Checksum: 62C4B8FC2D2C4CB1
Sequence:

MALAQQLRSE SDFEQLPDDV AVSANIADIE EKRGFTSHFV FVIEVKTKGG SKYLIYRRYR 
QFYALQSKLE ERFGPESKNS PFTCSLPTLP AKVYMGAKQE IAETRIPALN AYMKNLLSLP 
VCVLMDPDVR IFFYQSAYDA EQVPQALRRL RPRTRKIKGV SPQGAIMDRM EAPRAEALFD 
FTGNSKLELS FKAGDVIFLL SKINKDWLEG TSQGATGIFP GSFVKILKDF PEDEDTTNWL 
RCYFYEDTGK TIKDIAVEED LSSTPLFKDL LALMRREFQR EDIALSYQDA EGDLVRLLSD 
EDVGLMVKQA RGLPSQKRLF PWKLHVTQKD NYSVYNTVP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ncf4

Associated with

Other Information

Cloning and chromosomal localization of ncf4, the mouse homologue of p40-phox. PubMed ID: 8995189

Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex. PubMed ID: 9490028

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection. PubMed ID: 21551061