Genular: Defining Cellular Identity and Function

Details for: Nck2

Gene ID: 17974

Symbol: Nck2

Ensembl ID: ENSMUSG00000066877

Description: non-catalytic region of tyrosine kinase adaptor protein 2

Associated with

Axon guidance
(R-MMU-422475)
Cell-cell communication
(R-MMU-1500931)
Developmental biology
(R-MMU-1266738)
Downstream signal transduction
(R-MMU-186763)
Eph-ephrin signaling
(R-MMU-2682334)
Ephrin signaling
(R-MMU-3928664)
Nephrin family interactions
(R-MMU-373753)
Nervous system development
(R-MMU-9675108)
Rho gtpase cycle
(R-MMU-9012999)
Rhou gtpase cycle
(R-MMU-9013420)
Rhov gtpase cycle
(R-MMU-9013424)
Signaling by pdgf
(R-MMU-186797)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by vegf
(R-MMU-194138)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Actin filament organization
(GO:0007015)
Cell migration
(GO:0016477)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendritic spine development
(GO:0060996)
Endoplasmic reticulum
(GO:0005783)
Ephrin receptor signaling pathway
(GO:0048013)
Immunological synapse formation
(GO:0001771)
Lamellipodium assembly
(GO:0030032)
Negative regulation of endoplasmic reticulum stress-induced eif2 alpha phosphorylation
(GO:1903912)
Negative regulation of perk-mediated unfolded protein response
(GO:1903898)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Phosphotyrosine residue binding
(GO:0001784)
Positive regulation of actin filament polymerization
(GO:0030838)
Positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
(GO:1902237)
Positive regulation of peptidyl-serine dephosphorylation
(GO:1902310)
Positive regulation of t cell proliferation
(GO:0042102)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of translation in response to endoplasmic reticulum stress
(GO:0036493)
Postsynaptic density
(GO:0014069)
Protein-containing complex binding
(GO:0044877)
Receptor tyrosine kinase binding
(GO:0030971)
Regulation of translation
(GO:0006417)
Response to endoplasmic reticulum stress
(GO:0034976)
Scaffold protein binding
(GO:0097110)
Signaling adaptor activity
(GO:0035591)
Signal transduction
(GO:0007165)
Synapse
(GO:0045202)
Vesicle membrane
(GO:0012506)

Other Information

Proteins

Cytoplasmic protein NCK2
Q8BQ28_MOUSE

Genular Protein ID: 1595596800

Symbol: NCK2_MOUSE

Name: Cytoplasmic protein NCK2

UniProtKB Accession Codes:

O55033

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 380
Mass: 42879
Checksum: 7B3404B976F0A54D
Sequence:

MTEEVIVIAK WDYTAQQDQE LDIRKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN 
SLKKGSLVKN LKDTLGLGKT RRKPSARDAS PTPSTDAEYP ANGSGADRIY DLNIPAFVKF 
AYVAEREDEL SLVKGSRVTV MEKCSDGWWR GSFNGQIGWF PSNYVLEEAD EAAAEAPSFL 
SLRRGTALSN GQGARVLHVV QTLYPFSSVT EEELSFEKGE TMEVIEKPEN DPEWWKCKNA 
RGQVGLVPKN YVVVLSDGPA LHPAHTPQIS YTGPSASGRF AGREWYYGNV TRHQAECALN 
ERGVEGDFLI RDSESSPSDF SVSLKASGRN KHFKVQLVDS VYCIGQRRFH SMDELVEHYK 
KAPIFTSEHG EKLYLVRALQ

Genular Protein ID: 3937137347

Symbol: Q8BQ28_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BQ28

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 380
Mass: 42863
Checksum: 7B3404B976EA14E6
Sequence:

MTEEVIVIAK WDYTAQQDQE LDIRKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN 
SLKKGSLVKN LKDTLGLGKT RRKPSARDAS PTPSTDAEYP ANGSGADRIY DLNIPAFVKF 
AYVAEREDEL SLVKGSRVTV MEKCSDGWWR GSFNGQIGWF PSNYVLEEAD EAAAEAPSFL 
SLRRGTALSN GQGARVLHVV QTLYPFSSVT EEELSFEKGE TMEVIEKPEN DPEWWKCKNA 
RGQVGLVPKN YVVVLSDGPA LHPAHTPQIS YTGPSASGRF AGREWYYGNV TRHQAECALN 
ERGVEGDFLI RDSESSPSDF SVSLKASGRN KHFKVQLVDS VYSIGQRRFH SMDELVEHYK 
KAPIFTSEHG EKLYLVRALQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nck2

Associated with

Other Information

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. PubMed ID: 17947660

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073