Genular: Defining Cellular Identity and Function

Details for: Ndn

Gene ID: 17984

Symbol: Ndn

Ensembl ID: ENSMUSG00000033585

Description: necdin, MAGE family member

Associated with

Axonal fasciculation
(GO:0007413)
Axon extension
(GO:0048675)
Axonogenesis
(GO:0007409)
Cell projection
(GO:0042995)
Central nervous system development
(GO:0007417)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna binding
(GO:0003677)
Gamma-tubulin binding
(GO:0043015)
Genomic imprinting
(GO:0071514)
Glial cell migration
(GO:0008347)
Multicellular organismal-level homeostasis
(GO:0048871)
Negative regulation of dna-binding transcription factor activity
(GO:0043433)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron development
(GO:0048666)
Neuron differentiation
(GO:0030182)
Neuron migration
(GO:0001764)
Neurotrophin trk receptor signaling pathway
(GO:0048011)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of protein deacetylation
(GO:0090312)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Post-embryonic development
(GO:0009791)
Promoter-specific chromatin binding
(GO:1990841)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Respiratory gaseous exchange by respiratory system
(GO:0007585)
Respiratory system process
(GO:0003016)
Sensory perception of pain
(GO:0019233)

Other Information

Proteins

Necdin

Genular Protein ID: 2443937905

Symbol: NECD_MOUSE

Name: Necdin

UniProtKB Accession Codes:

P25233 B9EJJ5 Q542W7 Q61951

Database IDs:

Citations:

PubMed ID: 2069569

Title: A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells.

PubMed ID: 2069569

DOI: 10.1016/0006-291x(91)91812-q

PubMed ID: 8557705

Title: Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter.

PubMed ID: 8557705

DOI: 10.1074/jbc.271.2.918

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9422723

Title: Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1.

PubMed ID: 9422723

DOI: 10.1074/jbc.273.2.720

PubMed ID: 10347180

Title: Physical and functional interactions of neuronal growth suppressor necdin with p53.

PubMed ID: 10347180

DOI: 10.1074/jbc.274.23.16242

PubMed ID: 10965153

Title: Cellular and subcellular localization of necdin in fetal and adult mouse brain.

PubMed ID: 10965153

DOI: 10.1159/000017455

Sequence Information:

Length: 325
Mass: 36832
Checksum: 777385B0B75E443F
Sequence:

MSEQSKDLSD PNFAAEVPDC EMQDSDAVPV GIPPPASLAA NLAGPPCAPE GPMAAQQASP 
PPEERIEDVD PKILQQAAEE GRAHQPQSPA RPIPAPPAPA QLVQKAHELM WYVLVKDQKR 
MVLWFPDMVK EVMGSYKKWC RSILRRTSVI LARVFGLHLR LTNLHTMEFA LVKALSPEEL 
DRVALNNRMP MTGLLLMILS LIYVKGRGAR EGAVWNVLRI LGLRPWKKHS TFGDVRKIIT 
EEFVQQNYLK YQRVPHIEPP EYEFFWGSRA NREITKMQIM EFLARVFKKD PQAWPSRYRE 
ALEQARALRE ANLAAQAPRS SVSED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ndn

Associated with

Other Information

A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells. PubMed ID: 2069569

Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter. PubMed ID: 8557705

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1. PubMed ID: 9422723

Physical and functional interactions of neuronal growth suppressor necdin with p53. PubMed ID: 10347180

Cellular and subcellular localization of necdin in fetal and adult mouse brain. PubMed ID: 10965153