ABAT | ENSG00000183044 | NCBI 18

Details for: ABAT

Gene ID: 18

Symbol: ABAT

Ensembl ID: ENSG00000183044

Description: 4-aminobutyrate aminotransferase

Associated with

Degradation of gaba
(R-HSA-916853)
Gaba synthesis, release, reuptake and degradation
(R-HSA-888590)
Neuronal system
(R-HSA-112316)
Neurotransmitter release cycle
(R-HSA-112310)
Transmission across chemical synapses
(R-HSA-112315)
(s)-3-amino-2-methylpropionate transaminase activity
(GO:0047298)
4-aminobutyrate:2-oxoglutarate transaminase activity
(GO:0034386)
4-aminobutyrate transaminase activity
(GO:0003867)
4-aminobutyrate transaminase complex
(GO:0032144)
Behavioral response to cocaine
(GO:0048148)
Cerebellum development
(GO:0021549)
Copulation
(GO:0007620)
Exploration behavior
(GO:0035640)
Gamma-aminobutyric acid biosynthetic process
(GO:0009449)
Gamma-aminobutyric acid catabolic process
(GO:0009450)
Gamma-aminobutyric acid metabolic process
(GO:0009448)
Identical protein binding
(GO:0042802)
Iron-sulfur cluster binding
(GO:0051536)
Locomotory behavior
(GO:0007626)
Metal ion binding
(GO:0046872)
Mitochondrial matrix
(GO:0005759)
Mitochondrion
(GO:0005739)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of dopamine secretion
(GO:0033602)
Negative regulation of gamma-aminobutyric acid secretion
(GO:0014053)
Positive regulation of aspartate secretion
(GO:1904450)
Positive regulation of dopamine metabolic process
(GO:0045964)
Positive regulation of heat generation
(GO:0031652)
Positive regulation of inhibitory postsynaptic potential
(GO:0097151)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of prolactin secretion
(GO:1902722)
Positive regulation of uterine smooth muscle contraction
(GO:0070474)
Pyridoxal phosphate binding
(GO:0030170)
Response to ethanol
(GO:0045471)
Response to hypoxia
(GO:0001666)
Response to iron ion
(GO:0010039)
Response to nicotine
(GO:0035094)
Response to xenobiotic stimulus
(GO:0009410)
Succinate-semialdehyde dehydrogenase binding
(GO:0032145)

Other Information

Proteins

4-aminobutyrate aminotransferase, mitochondrial

Genular Protein ID: 3750774859

Symbol: GABT_HUMAN

Name: 4-aminobutyrate aminotransferase, mitochondrial

UniProtKB Accession Codes:

P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800

Database IDs:

Citations:

PubMed ID: 7721088

Title: Screening and sequence determination of a cDNA encoding the human brain 4-aminobutyrate aminotransferase.

PubMed ID: 7721088

DOI: 10.1016/0378-1119(94)00858-p

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7851425

Title: Primary structure and tissue distribution of human 4-aminobutyrate aminotransferase.

PubMed ID: 7851425

DOI: 10.1111/j.1432-1033.1995.tb20412.x

PubMed ID: 15528998

Title: Cysteine-321 of human brain GABA transaminase is involved in intersubunit cross-linking.

PubMed ID: 15528998

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10407778

Title: 4-aminobutyrate aminotransferase (GABA-transaminase) deficiency.

PubMed ID: 10407778

DOI: 10.1023/a:1005500122231

Sequence Information:

Length: 500
Mass: 56439
Checksum: F990B0B6B77BD3F5
Sequence:

MASMLLAQRL ACSFQHSYRL LVPGSRHISQ AAAKVDVEFD YDGPLMKTEV PGPRSQELMK 
QLNIIQNAEA VHFFCNYEES RGNYLVDVDG NRMLDLYSQI SSVPIGYSHP ALLKLIQQPQ 
NASMFVNRPA LGILPPENFV EKLRQSLLSV APKGMSQLIT MACGSCSNEN ALKTIFMWYR 
SKERGQRGFS QEELETCMIN QAPGCPDYSI LSFMGAFHGR TMGCLATTHS KAIHKIDIPS 
FDWPIAPFPR LKYPLEEFVK ENQQEEARCL EEVEDLIVKY RKKKKTVAGI IVEPIQSEGG 
DNHASDDFFR KLRDIARKHG CAFLVDEVQT GGGCTGKFWA HEHWGLDDPA DVMTFSKKMM 
TGGFFHKEEF RPNAPYRIFN TWLGDPSKNL LLAEVINIIK REDLLNNAAH AGKALLTGLL 
DLQARYPQFI SRVRGRGTFC SFDTPDDSIR NKLILIARNK GVVLGGCGDK SIRFRPTLVF 
RDHHAHLFLN IFSDILADFK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ABAT

Associated with

Other Information

Screening and sequence determination of a cDNA encoding the human brain 4-aminobutyrate aminotransferase. PubMed ID: 7721088

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Primary structure and tissue distribution of human 4-aminobutyrate aminotransferase. PubMed ID: 7851425

Cysteine-321 of human brain GABA transaminase is involved in intersubunit cross-linking. PubMed ID: 15528998

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

4-aminobutyrate aminotransferase (GABA-transaminase) deficiency. PubMed ID: 10407778